Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 19/20 | 0.60 |
| ▸ | PDE4B | Q07343 | 17/20 | 0.60 |
| ▸ | PDE4A | P27815 | 16/20 | 0.60 |
| ▸ | PDE4C | Q08493 | 16/20 | 0.60 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6822446 | 0.94 | PDE4D (0.67) | PDE4DPDE4BPDE4APDE4CMAPK14 | |
| SCHEMBL1026479 | 0.87 | PDE4D (0.62) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL6814857 | 0.83 | PDE4D (0.54) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL6818305 | 0.82 | PDE4D (0.69) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL3370223 | 0.81 | PDE4D (0.71) | PDE4DPDE4BPDE4APDE4CMAPK14 | |
| SCHEMBL71331 | 0.80 | PDE4D (0.65) | PDE4DPDE4BPDE4APDE4CMAPK14 | |
| SCHEMBL7353105 | 0.80 | PDE4D (0.49) | PDE4DPDE4BPDE4APDE4CMAPK14 | |
| SCHEMBL7336558 | 0.79 | PDE4D (0.64) | PDE4DPDE4BPDE4APDE4CMAPK14 | |
| SCHEMBL7360312 | 0.78 | PDE4D (0.68) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL7418490 | 0.78 | PDE4B (0.49) | PDE4DPDE4BPDE4APDE4CMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2044023-B1 | DERIVATIVES OF 1-PHENYL-2-PYRIDYNYL ALKYLENE ALCOHOLS AS PHOSPHODIESTERASE INHIBITORS | CHIESI FARMA SPA (IT) | 2011-01-19 | — | — | EP | disclosed |
| US-7671066-B2 | Derivatives of 1-phenyl-2-pyridynyl alkylene alcohols as phosphodiesterase inhibitors | CHIESI FARMACEUTICI S.P.A. (IT) | 2010-03-02 | — | — | US | disclosed |
| CN-101490004-A | Derivatives of 1-phenyl-2-pyridynyl alkylene alcohols as phosphodiesterase inhibitors | CHIESI FARMA S P A (IT) | 2009-07-22 | — | — | CN | disclosed |
| EP-2044023-A1 | DERIVATIVES OF 1-PHENYL-2-PYRIDYNYL ALKYLENE ALCOHOLS AS PHOSPHODIESTERASE INHIBITORS | CHIESI FARMACEUTICI S.p.A. (IT) | 2009-04-08 | — | — | EP | disclosed |
| WO-2008006509-A1 | DERIVATIVES OF 1-PHENYL-2-PYRIDYNYL ALKYLENE ALCOHOLS AS PHOSPHODIESTERASE INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2008-01-17 | — | — | WO | disclosed |
| US-20080015226-A1 | Derivatives of 1-phenyl-2-pyridynyl alkylene alcohols as phosphodiesterase inhibitors | CHIESI FARMACEUTICI S.P.A.. | 2008-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080015226-A1 | Derivatives of 1-phenyl-2-pyridynyl alkylene alcohols as phosphodiesterase inhibitors | PDE4A, PDE4B, PDE12 | PDE4D 9/4885PDE4B 2/4885PDE4A 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.