Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL7540197 | 0.94 | CALM1 (0.47) | CALM1TSHRALDH1A1LOXL2IDO1 | |
| Iodide SCHEMBL1032295 | 0.94 | CALM1 (0.47) | CALM1TSHRALDH1A1LOXL2IDO1 | |
| Bromide SCHEMBL5897988 | 0.94 | CALM1 (0.47) | CALM1TSHRALDH1A1LOXL2IDO1 | |
| Fluoride Ion SCHEMBL5897693 | 0.94 | CALM1 (0.47) | CALM1TSHRALDH1A1LOXL2IDO1 | |
| SCHEMBL11787603 | 0.94 | CALM1 (0.47) | CALM1TSHRALDH1A1LOXL2IDO1 | |
| Hydrochloric Acid SCHEMBL8855132 | 0.80 | CALM1 (0.41) | CALM1TSHRALDH1A1LOXL2IDO1 | |
| Hydrochloric Acid SCHEMBL2030983 | 0.77 | TP53 (0.42) | TP53TDP1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10523509 | 0.77 | TP53 (0.42) | TP53TDP1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10918024 | 0.75 | CALM1 (0.41) | CALM1TSHRALDH1A1LOXL2IDO1 | |
| Hydrochloric Acid SCHEMBL11682287 | 0.71 | ALDH1A1 (0.50) | CALM1TSHRALDH1A1LOXL2IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 135 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115382568-B | Preparation method and application of hydrophilic-lipophilic ZSM-5 catalyst | 神马实业股份有限公司 | 2024-03-12 | — | — | CN | claimed |
| CN-115382568-A | Preparation method and application of hydrophilic-lipophilic ZSM-5 catalyst | 神马实业股份有限公司 | 2022-11-25 | — | — | CN | claimed |
| CN-113025379-B | Coking inhibitor for advanced catalytic cracking olefin preparation device and preparation method thereof | 浙江杭化科技股份有限公司 | 2022-09-20 | — | — | CN | claimed |
| CN-110368976-B | Preparation method and application of tin-nitrogen-carbon quantum dot supported catalyst | 太原理工大学 | 2022-08-26 | — | — | CN | claimed |
| CN-113025379-A | Coking inhibitor for advanced catalytic cracking olefin preparation device and preparation method thereof | 浙江杭化科技股份有限公司 | 2021-06-25 | — | — | CN | claimed |
| CN-107442169-B | Catalyst loaded with chlorine-containing organotin and nitrogen-containing compound and preparation method and application thereof | 太原理工大学 | 2020-02-07 | — | — | CN | claimed |
| CN-110368976-A | A kind of preparation method and application of tin nitrogen carbon quantum dot loaded catalyst | 太原理工大学 | 2019-10-25 | — | — | CN | claimed |
| CN-105399765-B | A kind of 2 carbonyl propionic acid benzoyl hydrazone tribenzyltin complexs and its preparation method and application | 衡阳师范学院 | 2018-01-16 | — | — | CN | claimed |
| CN-105860095-B | Humic acid organotin carboxylate and its preparation method and application | 河南省科学院化学研究所有限公司 | 2018-01-05 | — | — | CN | claimed |
| CN-107442169-A | A kind of catalyst for loading chloride organotin and nitrogen-containing compound and its preparation method and application | 太原理工大学 | 2017-12-08 | — | — | CN | claimed |
| CN-102206311-A | Saturated polyester for sheet moulding compound or bulk molding compound (SMC/BMC) low-shrinking agent and preparation method thereof | Changzhou huake resin co ltd | 2011-10-05 | — | — | CN | claimed |
| CN-102040669-A | Preparation method of chitosan-based organo-tin compound | HUNAN INST SCIENCE & TECH | 2011-05-04 | — | — | CN | claimed |
| US-7008899-B2 | Lanthanide-based catalyst composition for producing cis-1,4-polydienes | BRIDGESTONE CORPORATION (JP) | 2006-03-07 | — | — | US | claimed |
| US-20050038215-A1 | Lanthanide-based catalyst composition for producing cis-1,4-polydienes | BRIDGESTONE CORPORATION (JP) | 2005-02-17 | — | — | US | claimed |
| EP-1208570-A1 | HIGH VOLTAGE CAPABLE NON-VOLATILE LOW VISCOSITY INSULATING RESINS | Siemens Westinghouse Power Corporation (US) | 2002-05-29 | — | — | EP | claimed |
| US-6384152-B2 | EPOXY RESINS | SIEMENS WESTINGHOUSE POWER CORPORATION | 2002-05-07 | — | — | US | claimed |
| US-20020010289-A1 | HIGH VOLTAGE CAPABLE NON-VOLATILE LOW VISCOSITY INSULATING RESINS | SIEMENS ENERGY, INC. | 2002-01-24 | — | — | US | claimed |
| WO-2001006520-A1 | HIGH VOLTAGE CAPABLE NON-VOLATILE LOW VISCOSITY INSULATING RESINS | SIEMENS WESTINGHOUSE POWER CORPORATION (US) | 2001-01-25 | — | — | WO | claimed |
| US-4828753-A | Storage-stable organic solutions of polyisocyanates | RHONE-POULENC SPECIALITIES CHIMIQUES (FR) | 1989-05-09 | — | — | US | claimed |
| US-4812525-A | MODIFIED WITH TIN COMPOUNDS; TIRES | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1989-03-14 | — | — | US | claimed |