Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 6/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MBTD1 | Q05BQ5 | 4/20 | 0.43 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1031602 | 0.90 | L3MBTL3 (0.54) | L3MBTL3L3MBTL1ALDH1A1KDM4EMBTD1 | |
| SCHEMBL1030954 | 0.83 | ALDH1A1 (0.48) | L3MBTL3L3MBTL1ALDH1A1HPGDKDM4E | |
| SCHEMBL12835172 | 0.80 | L3MBTL3 (0.73) | L3MBTL3L3MBTL1ALDH1A1HPGDKDM4E | |
| SCHEMBL15759144 | 0.79 | L3MBTL3 (0.75) | L3MBTL3L3MBTL1ALDH1A1HPGDKDM4E | |
| SCHEMBL17888342 | 0.76 | L3MBTL3 (0.70) | L3MBTL3L3MBTL1ALDH1A1KDM4EPOLB | |
| SCHEMBL12237822 | 0.73 | L3MBTL3 (0.65) | L3MBTL3L3MBTL1ALDH1A1HPGDKDM4E | |
| SCHEMBL1032266 | 0.73 | KDM4E (0.55) | L3MBTL3L3MBTL1ALDH1A1HPGDKDM4E | |
| SCHEMBL1032819 | 0.73 | TSHR (0.59) | ALDH1A1KMT2A | |
| SCHEMBL1027632 | 0.73 | L3MBTL3 (0.51) | L3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL12237814 | 0.72 | L3MBTL3 (0.69) | L3MBTL3L3MBTL1ALDH1A1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2035375-B1 | 1,3-DISUBSTITUTED 4-METHYL-1H-PYRROLE-2-CARBOXAMIDES AND THEIR USE FOR THE MANUFACTURE OF MEDICAMENTS | GRUENENTHAL GMBH (DE) | 2011-01-19 | — | — | EP | claimed |