Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10309752 | 0.89 | RAB9A (0.45) | ALDH1A1HPGDSMN1; SMN2LMNAPOLB | |
| SCHEMBL7208339 | 0.89 | ADORA3 (0.48) | ALDH1A1SMN1; SMN2LMNAPOLBTSHR | |
| SCHEMBL7205483 | 0.88 | TOP2A (0.45) | ALDH1A1HPGDSMN1; SMN2LMNAMAPT | |
| SCHEMBL7205773 | 0.87 | TLR7 (0.48) | ALDH1A1POLBMAPTPTGDR2TDP1 | |
| SCHEMBL2060205 | 0.86 | ADORA3 (0.40) | ALDH1A1HPGDSMN1; SMN2LMNAPOLB | |
| SCHEMBL2060430 | 0.86 | SMN1; SMN2 (0.52) | ALDH1A1HPGDSMN1; SMN2LMNAPOLB | |
| SCHEMBL7210357 | 0.84 | DRD2 (0.46) | ALDH1A1SMN1; SMN2MAPTADORA3NPC1 | |
| SCHEMBL2060384 | 0.84 | TLR7 (0.43) | ALDH1A1SMN1; SMN2MAPTTSHRGAA | |
| SCHEMBL2060176 | 0.84 | DRD2 (0.51) | ALDH1A1HPGDSMN1; SMN2LMNAPOLB | |
| SCHEMBL7209553 | 0.83 | TSHR (0.44) | ALDH1A1HPGDPOLBMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120178743-A1 | NOVEL ADENINE COMPOUND AND USE THEREOF | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2012-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120178743-A1 | NOVEL ADENINE COMPOUND AND USE THEREOF | ADORA1, HRH4, P2RY10 | ALDH1A1 875/4885HPGD 449/4885SMN1; SMN2 4605/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.