Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALDH1A3 | P47895 | 3/20 | 0.42 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.42 |
| ▸ | PRKDC | P78527 | 2/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10310114 | 0.94 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL19176232 | 0.74 | ALDH1A1 (0.49) | ALDH1A1LMNAMEN1KMT2APRKDC | |
| SCHEMBL19170774 | 0.71 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL16464268 | 0.71 | ALDH1A1 (0.73) | ALDH1A1SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL417908 | 0.71 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL16577084 | 0.71 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL13503416 | 0.70 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL10175274 | 0.70 | GAA (0.47) | ALDH1A1LMNAMEN1KMT2AATM | |
| SCHEMBL11339430 | 0.69 | USP2 (0.45) | ALDH1A1SMN1; SMN2LMNAPRKDCALOX15 | |
| SCHEMBL19030626 | 0.68 | LGMN (0.48) | ALDH1A1LMNAPIK3CAALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120178743-A1 | NOVEL ADENINE COMPOUND AND USE THEREOF | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2012-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120178743-A1 | NOVEL ADENINE COMPOUND AND USE THEREOF | ADORA1, HRH4, P2RY10 | ALDH1A1 875/4885SMN1; SMN2 4605/4885LMNA 4453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.