Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | PRKDC | P78527 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19170717 | 0.83 | ALDH1A1 (0.49) | ALDH1A1HPGDL3MBTL1NPC1TSHR | |
| SCHEMBL24202815 | 0.83 | ALDH1A1 (0.44) | ALDH1A1HPGDL3MBTL1LMNATSHR | |
| SCHEMBL13503416 | 0.80 | ALDH1A1 (0.62) | ALDH1A1HSD17B10ALOX15HPGDLMNA | |
| SCHEMBL19170774 | 0.79 | ALDH1A1 (0.51) | ALDH1A1HSD17B10ALOX15HPGDPRKDC | |
| SCHEMBL10310114 | 0.78 | ALDH1A1 (0.49) | ALDH1A1HSD17B10ALOX15HPGDATM | |
| SCHEMBL12875592 | 0.76 | CYP2A13 (0.51) | ALDH1A1PKMPRKDCLMNATSHR | |
| SCHEMBL2821701 | 0.76 | P2RX7 (0.51) | ALDH1A1PKMHPGDPRKDCL3MBTL1 | |
| SCHEMBL16363805 | 0.76 | GAA (0.53) | ALDH1A1HPGDL3MBTL1LMNATSHR | |
| SCHEMBL24992291 | 0.75 | ALDH3A1 (0.45) | ALDH1A1PKMHSD17B10ALOX15HPGD | |
| SCHEMBL24630249 | 0.75 | MAPT (0.61) | ALDH1A1ATML3MBTL1LMNANSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170209591-A1 | MAYTANSINOID DERIVATIVES, CONJUGATES THEREOF, AND METHODS OF USE | REGENERON PHARMACEUTICALS, INC. | 2017-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170209591-A1 | MAYTANSINOID DERIVATIVES, CONJUGATES THEREOF, AND METHODS OF USE | HNMT, SLC10A1, SLC10A2 | ALDH1A1 331/4885PKM 2662/4885HSD17B10 1309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.