SCHEMBL1031026

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1034164	0.89	SIRT2 (0.54)	ATRPOLBGLANPSR1NPC1
	SCHEMBL1036245	0.87	ATR (0.58)	ATRCHRNB2CHRNB4CHRNA3CHRNA4
	SCHEMBL1035668	0.86	CYP1A2 (0.55)	ATRCHRNB2CHRNB4CHRNA3CHRNA4
	SCHEMBL1031251	0.86	SIRT2 (0.56)	CHRNB2CHRNB4CHRNA3CHRNA4POLB
	SCHEMBL1034842	0.86	SIRT2 (0.51)	ATRPOLBGLANPSR1NPC1
	SCHEMBL1035333	0.85	SMN1; SMN2 (0.57)	POLBNPC1RAB9AMEN1KMT2A
	SCHEMBL1030075	0.85	FGFR4 (0.48)	POLBNPC1RAB9ACYP1A2CYP2D6
	SCHEMBL1033357	0.85	KMT2A (0.53)	KMT2AALDH1A1
	SCHEMBL1031934	0.83	EGLN1 (0.60)	POLBNPC1RAB9AMEN1KMT2A
	SCHEMBL1033871	0.83	FGFR4 (0.51)	CHRNB2CHRNB4CHRNA3CHRNA4NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.