SCHEMBL1036245

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1031026	0.87	ATR (0.57)	ATRCHRNB2CHRNB4CHRNA3CHRNA4
	SCHEMBL1035756	0.87	CYP1A2 (0.55)	ATRCHRNB2CHRNB4CHRNA3CHRNA4
	SCHEMBL1034164	0.86	SIRT2 (0.54)	ATRCYP2C9CYP1A2CYP2D6CYP2C19
	SCHEMBL1035333	0.84	SMN1; SMN2 (0.57)	CYP2C9CYP1A2CYP2D6CYP2C19CYP3A4
	SCHEMBL1030075	0.84	FGFR4 (0.48)	CYP2C9CYP1A2CYP2D6CYP2C19CYP3A4
	SCHEMBL1035234	0.84	MPL (0.52)	ATRCHRNB2CHRNB4CHRNA3CHRNA4
	SCHEMBL1034318	0.84	FGFR4 (0.53)	ATRCHRNB2CHRNB4CHRNA3CHRNA4
	SCHEMBL1034242	0.83	ALDH1A1 (0.54)	ATRCYP2C9ALDH1A1PARP1EGLN1
	SCHEMBL1034842	0.83	SIRT2 (0.51)	ATRCYP2C9CYP1A2CYP2D6CYP2C19
	SCHEMBL1031934	0.82	EGLN1 (0.60)	CYP2C9SMN1; SMN2POLBALDH1A1EGLN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.