SCHEMBL1031251

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1034164	0.94	SIRT2 (0.54)	SIRT2PARP1ALDH1A1SMN1; SMN2RAB9A
	SCHEMBL1031026	0.86	ATR (0.57)	SIRT2PARP1ALDH1A1SMN1; SMN2RAB9A
	SCHEMBL1034603	0.85	ALOX15 (0.59)	SIRT2PARP1SMN1; SMN2RAB9ANPSR1
	SCHEMBL1032899	0.83	SIRT2 (0.51)	SIRT2RAB9AABL1NPSR1TSHR
	SCHEMBL1033827	0.82	KMT2A (0.52)	SIRT2ALDH1A1SMN1; SMN2RAB9ACYP2C9
	SCHEMBL1032623	0.81	ATR (0.47)	SIRT2RAB9A
	SCHEMBL1036245	0.81	ATR (0.58)	PARP1ALDH1A1SMN1; SMN2CHRNB2CHRNB4
	SCHEMBL1035548	0.80	PARP1 (0.65)	PARP1ALDH1A1RAB9ACHRNB2CHRNB4
	SCHEMBL1034842	0.79	SIRT2 (0.51)	SIRT2PARP1ALDH1A1SMN1; SMN2RAB9A
	SCHEMBL1030075	0.79	FGFR4 (0.48)	ALDH1A1SMN1; SMN2RAB9AABL1BCR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.