SCHEMBL10310337

SCHEMBL10310337

c1ccc(Oc2ccc(-n3c4ccccc4c4cc(-c5ccc6c(c5)c5ccccc5n6-c5ccc(-c6ccc(N(c7ccccc7)c7ccccc7)cc6)cc5)ccc43)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.41
ATM Q13315 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
TSPO P30536 6/20 0.40
ICMT O60725 5/20 0.38
PTPN1 P18031 1/20 0.37
HDAC4 P56524 1/20 0.36
SCN9A Q15858 2/20 0.36
NTRK1 P04629 1/20 0.35
IGF1R P08069 1/20 0.35
FGFR1 P11362 1/20 0.35
NTRK3 Q16288 1/20 0.35
NTRK2 Q16620 1/20 0.35
EDNRA P25101 1/20 0.35
MAP4K1 Q92918 1/20 0.34
USP14 P54578 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8928141 0.91 KDM4E (0.46) KDM4EATML3MBTL1TSPOICMT
SCHEMBL10309939 0.91 KDM4E (0.50) KDM4EATML3MBTL1TSPOPTPN1
SCHEMBL15306423 0.90 L3MBTL1 (0.53) KDM4EATML3MBTL1TSPOPTPN1
SCHEMBL14183847 0.90 L3MBTL1 (0.49) KDM4EATML3MBTL1TSPOPTPN1
SCHEMBL13969285 0.90 L3MBTL1 (0.53) KDM4EATML3MBTL1TSPOPTPN1
SCHEMBL10004856 0.90 L3MBTL1 (0.53) KDM4EATML3MBTL1TSPOPTPN1
SCHEMBL15306455 0.90 L3MBTL1 (0.53) KDM4EATML3MBTL1TSPOPTPN1
SCHEMBL10309971 0.90 L3MBTL1 (0.49) KDM4EATML3MBTL1TSPOPTPN1
SCHEMBL13130948 0.90 L3MBTL1 (0.49) KDM4EATML3MBTL1TSPOPTPN1
SCHEMBL13803226 0.90 L3MBTL1 (0.49) KDM4EATML3MBTL1TSPOPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9732036-B2 Compound having carbazole ring structure, and organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2017-08-15 US disclosed
US-20120175599-A1 COMPOUND HAVING CARBAZOLE RING STRUCTURE, AND ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2012-07-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120175599-A1 COMPOUND HAVING CARBAZOLE RING STRUCTURE, AND ORGANIC ELECTROLUMINESCENT DEVICE POU5F1, POU2F1, KCNH3 KDM4E 1981/4885ATM 4605/4885L3MBTL1 783/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.