Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | NCF1 | P14598 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31599195 | 0.85 | LOXL2 (0.67) | LOXL2CYP1A2NCF1HTR1AADRA1D | |
| SCHEMBL334360 | 0.85 | LOXL2 (0.67) | LOXL2CYP1A2NCF1HTR1AADRA1D | |
| Bromide SCHEMBL9399386 | 0.83 | LOXL2 (0.64) | LOXL2CYP1A2NCF1HTR1AADRA1D | |
| SCHEMBL6176955 | 0.80 | LOXL2 (0.60) | LOXL2CYP1A2NCF1HTR1AADRA1D | |
| SCHEMBL7358307 | 0.77 | LOXL2 (0.56) | LOXL2CYP1A2NCF1HTR1AADRA1D | |
| SCHEMBL6112363 | 0.75 | LOXL2 (0.64) | LOXL2CYP1A2NCF1HTR1AADRA1D | |
| SCHEMBL996284 | 0.75 | LOXL2 (0.64) | LOXL2CYP1A2NCF1HTR1AADRA1D | |
| SCHEMBL13067165 | 0.75 | LOXL2 (0.64) | LOXL2CYP1A2NCF1HTR1AADRA1D | |
| SCHEMBL17266358 | 0.75 | LOXL2 (0.64) | LOXL2CYP1A2NCF1HTR1AADRA1D | |
| SCHEMBL3817375 | 0.75 | LOXL2 (0.64) | LOXL2CYP1A2NCF1HTR1AADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120178717-A1 | 4-QUINOLINEMETHANOLS AS ANTI-MALARIAL AGENTS | JENRIN DISCOVERY (US) | 2012-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120178717-A1 | 4-QUINOLINEMETHANOLS AS ANTI-MALARIAL AGENTS | CYP51A1, SQLE, NQO2 | LOXL2 4312/4885CYP1A2 65/4885NCF1 2389/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.