Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25934356 | 0.81 | PTPRC (0.45) | PTPRCALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL27346900 | 0.77 | ALDH1A1 (0.48) | PTPRCALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL2407584 | 0.76 | ALDH1A1 (0.57) | ALDH1A1MAPTLMNASMN1; SMN2NPC1 | |
| SCHEMBL16900338 | 0.75 | PTPRC (0.53) | PTPRCALDH1A1MAPTLMNAMAPK1 | |
| 1,2-Naphthoquinone SCHEMBL27704185 | 0.74 | MAPT (0.61) | PTPRCALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL3725061 | 0.72 | SLC7A5 (0.51) | PTPRCKDM4EPKMALOX15RECQL | |
| Naphthoquinone SCHEMBL28086193 | 0.71 | ALDH1A1 (0.83) | ALDH1A1MAPTLMNASMN1; SMN2NPC1 | |
| SCHEMBL11892894 | 0.71 | SMN1; SMN2 (0.80) | ALDH1A1MAPTLMNASMN1; SMN2NPC1 | |
| SCHEMBL19396241 | 0.71 | SMN1; SMN2 (0.88) | ALDH1A1MAPTLMNASMN1; SMN2NPC1 | |
| SCHEMBL11881427 | 0.71 | SMN1; SMN2 (0.88) | ALDH1A1MAPTLMNASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120178752-A1 | RHO KINASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120178752-A1 | RHO KINASE INHIBITORS | ROCK1, ROCK2, RHOA | PTPRC 847/4885ALDH1A1 2643/4885MAPT 791/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.