Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10311345 | 0.81 | PTPRC (0.53) | PTPRCLMNAMAPTALDH1A1MEN1 | |
| SCHEMBL3725061 | 0.77 | SLC7A5 (0.51) | PTPRCKDM4EPKMALOX15RECQL | |
| SCHEMBL18639800 | 0.72 | GABRA1 (0.47) | LMNAMAPTALDH1A1MEN1POLB | |
| SCHEMBL233251 | 0.72 | NPC1 (0.67) | LMNAMAPTALDH1A1MEN1POLB | |
| SCHEMBL19301850 | 0.71 | PTPRC (0.47) | PTPRCLMNAMAPTALDH1A1MEN1 | |
| SCHEMBL16900338 | 0.71 | PTPRC (0.53) | PTPRCLMNAMAPTALDH1A1MEN1 | |
| SCHEMBL28689696 | 0.70 | NPC1 (0.65) | PTPRCLMNAMAPTALDH1A1MEN1 | |
| SCHEMBL20888346 | 0.70 | LMNA (0.46) | LMNAMAPTALDH1A1MEN1POLB | |
| SCHEMBL19465353 | 0.68 | PTPRC (0.58) | PTPRCLMNAMAPTALDH1A1MEN1 | |
| SCHEMBL2525379 | 0.67 | PTPRC (0.52) | PTPRCLMNAMAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230242969-A1 | PEPTIDE NUCLEIC ACID FUNCTIONALIZED HYDROGEL MICRONEEDLES FOR SAMPLING AND DETECTION OF INTERSTITIAL FLUID NUCLEIC ACIDS | HOWARD HUGHES MEDICAL INSTITUTE | 2023-08-03 | — | — | US | disclosed |