Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | FBP1 | P09467 | 2/20 | 0.33 |
| ▸ | PHGDH | O43175 | 1/20 | 0.33 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
| ▸ | KDM4A | O75164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4011185 | 0.98 | F2 (0.41) | F2EPHX2L3MBTL1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL15212474 | 0.96 | F2 (0.39) | F2EPHX2L3MBTL1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL21359993 | 0.96 | F2 (0.39) | F2EPHX2L3MBTL1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL3788280 | 0.96 | F2 (0.39) | F2EPHX2L3MBTL1MEN1KMT2A | |
| Water SCHEMBL28947683 | 0.96 | F2 (0.39) | F2EPHX2L3MBTL1MEN1KMT2A | |
| SCHEMBL25590732 | 0.81 | HTR1A (0.42) | TDP1MGLLALDH1A1PHGDH | |
| SCHEMBL20752396 | 0.79 | CYP3A4 (0.42) | MEN1KMT2AMGLLALDH1A1PHGDH | |
| SCHEMBL1106418 | 0.77 | F2 (0.46) | F2MGLLALDH1A1FBP1PHGDH | |
| Hydrochloric Acid SCHEMBL28539659 | 0.75 | ALDH1A1 (0.41) | F2MEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL3027913 | 0.75 | F2 (0.32) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8377974-B2 | Factor Xa inhibitors | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2013-02-19 | — | — | US | disclosed |
| US-20120178733-A1 | FACTOR XA INHIBITORS | MILLENNIUM PHARMACEUTICALS, INC. | 2012-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120178733-A1 | FACTOR XA INHIBITORS | TFPI, F12, F11 | F2 5/4885EPHX2 497/4885L3MBTL1 3511/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.