Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | ERN1 | O75460 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 8/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | GAA | P10253 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 7/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.57 |
| ▸ | HTT | P42858 | 5/20 | 0.57 |
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | FNTA | P49354 | 1/20 | 0.53 |
| ▸ | FNTB | P49356 | 1/20 | 0.53 |
| ▸ | XBP1 | P17861 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1031373 | 1.00 | POLB (0.64) | POLBERN1MAPTALDH1A1GAA | |
| Bromide SCHEMBL6531580 | 0.97 | POLB (0.61) | POLBERN1MAPTALDH1A1GAA | |
| SCHEMBL14354139 | 0.92 | POLB (0.59) | POLBERN1MAPTALDH1A1GAA | |
| SCHEMBL14354141 | 0.92 | POLB (0.59) | POLBERN1MAPTALDH1A1GAA | |
| SCHEMBL16627922 | 0.91 | POLB (0.62) | POLBERN1MAPTALDH1A1GAA | |
| SCHEMBL27558820 | 0.91 | MAPT (0.60) | POLBERN1MAPTALDH1A1GAA | |
| SCHEMBL5728986 | 0.90 | POLB (0.60) | POLBERN1MAPTALDH1A1GAA | |
| SCHEMBL6742183 | 0.87 | MAPT (0.56) | POLBERN1MAPTALDH1A1GAA | |
| SCHEMBL8561665 | 0.86 | MAPT (0.55) | POLBERN1MAPTALDH1A1GAA | |
| SCHEMBL8561663 | 0.86 | MAPT (0.55) | POLBERN1MAPTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150080581-A1 | MULTICOORDINATED METAL COMPLEXES FOR USE IN METATHESIS REACTIONS | RIMTEC CORPORATION (JP) | 2015-03-19 | — | — | US | disclosed |
| US-8927670-B2 | Multicoordinated metal complexes for use in metathesis reactions | RIMTEC CORPORATION (JP) | 2015-01-06 | — | — | US | disclosed |
| EP-1577282-B1 | Metal complexes for use in olefin metathesis and atom or group transfer reactions | TELENE SAS (FR) | 2011-06-15 | — | — | EP | disclosed |
| EP-1757613-B1 | Multicoordinated metal complexes for use in metathesis reactions | TELENE SAS (FR) | 2011-01-19 | — | — | EP | disclosed |
| US-20080293905-A9 | MULTICOORDINATED METAL COMPLEXES FOR USE IN METATHESIS REACTIONS | RIMTEC CORPORATION (JP) | 2008-11-27 | — | — | US | disclosed |
| US-20070185343-A1 | Metal complexes for use in olefin metathesis and atom group transfer reactions | UNIVERSITEIT GENT (BE) | 2007-08-09 | — | — | US | disclosed |
| EP-1757613-A1 | Multicoordinated metal complexes for use in metathesis reactions | Viacatt N.V. (BE) | 2007-02-28 | — | — | EP | disclosed |
| US-20070043188-A1 | MULTICOORDINATED METAL COMPLEXES FOR USE IN METATHESIS REACTIONS | TELENE S.A.S. (FR) | 2007-02-22 | — | — | US | disclosed |
| EP-1577282-A2 | Metal complexes for use in olefin methathesis and atom or group transfer reactions | Universiteit Gent (BE) | 2005-09-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185343-A1 | Metal complexes for use in olefin metathesis and atom group transfer reactions | ME1, ME3, COASY | POLB 511/4885ERN1 3356/4885MAPT 1975/4885 |
| US-20150080581-A1 | MULTICOORDINATED METAL COMPLEXES FOR USE IN METATHESIS REACTIONS | APEX1, SOD1, AP1M1 | POLB 407/4885ERN1 3555/4885MAPT 3390/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.