Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.35 |
| ▸ | TTK | P33981 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4568166 | 0.85 | PTGER1 (0.49) | PPARGPTGER1 | |
| SCHEMBL4568131 | 0.82 | PTGER1 (0.43) | MEN1KMT2APPARGSMN1; SMN2PTGER1 | |
| SCHEMBL4568142 | 0.74 | PTGER1 (0.46) | MEN1KMT2APTGER1 | |
| SCHEMBL4568124 | 0.73 | MEN1 (0.44) | MEN1KMT2APTGER1ALDH1A1MAPT | |
| SCHEMBL15975091 | 0.71 | MEN1 (0.41) | MEN1KMT2APTGER1ALDH1A1 | |
| SCHEMBL4568164 | 0.69 | ENPP2 (0.48) | PTGER1 | |
| SCHEMBL15975188 | 0.69 | PDE10A (0.42) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL11979705 | 0.69 | PDE10A (0.38) | MEN1KMT2ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL4568149 | 0.68 | ENPP2 (0.59) | PTGER1 | |
| SCHEMBL4568125 | 0.67 | ENPP2 (0.49) | PTGER1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2474530-A1 | INDOLE DERIVATIVE AND PHARMACOLOGICALLY ACCEPTABLE SALT THEREOF | Kissei Pharmaceutical Co., Ltd. (JP) | 2012-07-11 | — | — | EP | disclosed |