SCHEMBL10314652

SCHEMBL10314652

C=CC(=O)Oc1ccc(OC(=O)C=C)c(F)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 4/20 0.44
TYMS P04818 1/20 0.38
MAPK1 P28482 3/20 0.37
POLB P06746 1/20 0.37
TSHR P16473 1/20 0.37
THRA P10827 1/20 0.37
LMNA P02545 2/20 0.35
HTT P42858 1/20 0.35
RAB9A P51151 1/20 0.35
FAAH O00519 3/20 0.34
ESR1 P03372 1/20 0.34
ESR2 Q92731 1/20 0.34
EGFR P00533 2/20 0.33
FFAR1 O14842 1/20 0.33
PPARG P37231 1/20 0.33
PPARD Q03181 1/20 0.33
KMT2A Q03164 3/20 0.33
ALDH1A1 P00352 3/20 0.33
MEN1 O00255 2/20 0.33
HPGD P15428 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28370101 0.90 CPS1 (0.43) THRBMAPK1LMNAHTTRAB9A
SCHEMBL28365704 0.88 LMNA (0.50) THRBMAPK1LMNAHTTRAB9A
SCHEMBL9607784 0.88 ESR1 (0.39) THRBTYMSLMNAESR1ESR2
SCHEMBL11237569 0.88 PPARG (0.48) THRBTHRAFAAHFFAR1PPARG
SCHEMBL9613625 0.87 THRB (0.43) THRBTYMSMAPK1POLBTSHR
SCHEMBL14984620 0.86 TSHR (0.46) THRBTYMSMAPK1POLBTSHR
SCHEMBL20672252 0.86 PPARD (0.38) THRBEGFRFFAR1PPARGPPARD
SCHEMBL9607776 0.86 ERN1 (0.40) THRBTYMSMAPK1POLBTSHR
SCHEMBL7417795 0.86 TSHR (0.49) THRBTYMSMAPK1POLBTSHR
SCHEMBL10181525 0.85 THRB (0.46) THRBMAPK1RAB9AESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120177847-A1 LIQUID CRYSTAL DISPLAY DEVICE AND METHOD OF PRODUCING THE SAME SHARP KABUSHIKI KAISHA (JP) 2012-07-12 US disclosed
US-20070206129-A1 Liquid crystal display device and method of producing the same NAKAMURA KIMIAKI 2007-09-06 US disclosed
US-7248318-B2 Liquid crystal display device and method of producing the same SHARP KABUSHIKI KAISHA (JP) 2007-07-24 US disclosed