Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | LPAR3 | Q9UBY5 | 7/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 6/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | CDC25A | P30304 | 1/20 | 0.30 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.30 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL251880 | 0.87 | LPAR3 (0.58) | TP53TDP1CYP3A4LPAR3LPAR2 | |
| SCHEMBL9685526 | 0.87 | TP53 (0.40) | TP53TDP1CYP3A4LPAR3LPAR2 | |
| SCHEMBL30946964 | 0.86 | TP53 (0.56) | TP53TDP1CYP3A4ALDH1A1 | |
| SCHEMBL10933894 | 0.85 | — | — | |
| SCHEMBL25170776 | 0.84 | LPAR3 (0.61) | TP53TDP1CYP3A4LPAR3LPAR2 | |
| SCHEMBL7550122 | 0.84 | LPAR3 (0.61) | TP53TDP1CYP3A4LPAR3LPAR2 | |
| SCHEMBL11292820 | 0.84 | TP53 (0.39) | TP53TDP1CYP3A4LPAR3LPAR2 | |
| SCHEMBL8674267 | 0.84 | TP53 (0.39) | TP53TDP1CYP3A4LPAR3LPAR2 | |
| SCHEMBL11290063 | 0.84 | LPAR3 (0.61) | TP53TDP1CYP3A4LPAR3LPAR2 | |
| SCHEMBL10597981 | 0.84 | TP53 (0.39) | TP53TDP1CYP3A4LPAR3LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2476685-B1 | Method for manufacturing alkyl-phosphates | LANXESS DEUTSCHLAND GMBH (DE) | 2017-08-02 | — | — | EP | disclosed |
| EP-2476684-B1 | Method for manufacturing alkyl-phosphates | LANXESS DEUTSCHLAND GMBH (DE) | 2017-07-19 | — | — | EP | disclosed |
| US-8846967-B2 | Process for preparing alkyl phosphates | LANXESS DEUTSCHLAND GMBH (DE) | 2014-09-30 | — | — | US | disclosed |
| EP-2479178-A1 | Process for the preparation of alkylphosphates | LANXESS Deutschland GmbH (DE) | 2012-07-25 | — | — | EP | disclosed |
| EP-2479179-A1 | Process for the preparation of alkylphosphates | LANXESS Deutschland GmbH (DE) | 2012-07-25 | — | — | EP | disclosed |
| US-20120184764-A1 | Process for preparing alkyl phosphates | LANXESS DEUTSCHLAND GMBH (DE) | 2012-07-19 | — | — | US | disclosed |
| US-20120184765-A1 | Process for preparing alkyl phosphates | LANXESS DEUTSCHLAND GMBH (DE) | 2012-07-19 | — | — | US | disclosed |
| US-20120184766-A1 | Process for preparing alkyl phosphates | LANXESS DEUTSCHLAND GMBH (DE) | 2012-07-19 | — | — | US | disclosed |
| EP-2476684-A1 | Method for manufacturing alkyl-phosphates | Lanxess Deutschland GmbH (DE) | 2012-07-18 | — | — | EP | disclosed |
| EP-2476685-A1 | Method for manufacturing alkyl-phosphates | Lanxess Deutschland GmbH (DE) | 2012-07-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120184764-A1 | Process for preparing alkyl phosphates | PNKP, PHOSPHO1, DCTPP1 | TP53 3358/4885TDP1 1821/4885CYP3A4 2486/4885 |
| US-20120184766-A1 | Process for preparing alkyl phosphates | PHOSPHO1, PNKP, PLCB3 | TP53 4006/4885TDP1 1594/4885CYP3A4 1968/4885 |
| US-20120184765-A1 | Process for preparing alkyl phosphates | PNKP, PHOSPHO1, DCTPP1 | TP53 3358/4885TDP1 1821/4885CYP3A4 2486/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.