Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.32 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11292820 | 0.98 | TP53 (0.39) | TP53TDP1LPAR3LPAR1LPAR2 | |
| SCHEMBL9530571 | 0.98 | TP53 (0.39) | TP53TDP1LPAR3LPAR1LPAR2 | |
| SCHEMBL10597981 | 0.98 | TP53 (0.39) | TP53TDP1LPAR3LPAR1LPAR2 | |
| SCHEMBL8674267 | 0.98 | TP53 (0.39) | TP53TDP1LPAR3LPAR1LPAR2 | |
| SCHEMBL10708258 | 0.92 | — | — | |
| SCHEMBL10316593 | 0.87 | TP53 (0.50) | TP53TDP1LPAR3LPAR1LPAR2 | |
| SCHEMBL11665213 | 0.83 | LPAR3 (0.35) | LPAR3LPAR1LPAR2CYP3A4 | |
| SCHEMBL10598471 | 0.83 | LPAR3 (0.35) | LPAR3LPAR1LPAR2CYP3A4 | |
| SCHEMBL93503 | 0.81 | — | — | |
| SCHEMBL10598475 | 0.79 | LPAR3 (0.42) | LPAR3LPAR1LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145844-A | Enzyme inhibitors, antiinflammatory agents, analgesics | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-09-08 | — | — | US | disclosed |
| US-5036152-A | Antiinflammatory | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1991-07-30 | — | — | US | disclosed |
| US-5030733-A | Analgesics, antiinflammatory agents, phospholipase inhibitor | HOECHST-ROUSSEL PHARMACETICALS INCORPORATED (US) | 1991-07-09 | — | — | US | disclosed |
| US-4891363-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | SANKYO COMPANY LIMITED (JP) | 1990-01-02 | — | — | US | disclosed |
| US-4888328-A | Alkoxycarbonylalkylphospholipids and alkylaminocarbonylalkylphospholipids | HOESCHST-ROUSSEL INCORPORATED (US) | 1989-12-19 | — | — | US | disclosed |
| EP-0332129-A2 | Alkoxy- and alkylamino-carbonylalkylphospholipids, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1989-09-13 | — | — | EP | disclosed |
| EP-0210804-B1 | PHOSPHATE ESTER DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE | SANKYO COMPANY LIMITED (JP) | 1989-05-10 | — | — | EP | disclosed |
| EP-0184905-B1 | 2-ACETOACETYLGLYCEROL DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1989-03-01 | — | — | EP | disclosed |
| US-4710579-A | ANTITUMOR AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1987-12-01 | — | — | US | disclosed |
| EP-0210804-A1 | Phosphate ester derivatives, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1987-02-04 | — | — | EP | disclosed |
| EP-0107120-B1 | SUBSTITUTED AMINOALCANOL PHOSPHOLIPIDS AND PROCESS FOR THEIR PREPARATION | A. Nattermann & Cie. GmbH (DE) | 1986-10-29 | — | — | EP | disclosed |
| EP-0121088-B1 | NEW O-ACYL-ALKANEDIOL-PHOSPHOLIPIDS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM | A. Nattermann & Cie. GmbH (DE) | 1986-10-01 | — | — | EP | disclosed |
| US-4610979-A | O-acyl-alkanediol-phospholipids and processes for the treatment of asthma | A. NATTERMANN & CIE GMBH (DE) | 1986-09-09 | — | — | US | disclosed |
| EP-0184905-A1 | 2-Acetoacetylglycerol derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1986-06-18 | — | — | EP | disclosed |
| US-4565659-A | Substituted aminoalkanol phospholipids | A. NATTERMANN & CIE GMBH (DE) | 1986-01-21 | — | — | US | disclosed |
| EP-0121088-A1 | New o-acyl-alkanediol-phospholipids, processes for their preparation and pharmaceutical preparations containing them | A. Nattermann & Cie. GmbH (DE) | 1984-10-10 | — | — | EP | disclosed |
| EP-0107120-A1 | Substituted aminoalcanol phospholipids and process for their preparation | A. Nattermann & Cie. GmbH (DE) | 1984-05-02 | — | — | EP | disclosed |