Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10355817 | 1.00 | CSNK2A1 (0.45) | CSNK2A1MAPTHTTHPGDKDM4E | |
| SCHEMBL10316745 | 1.00 | CSNK2A1 (0.45) | CSNK2A1MAPTHTTHPGDKDM4E | |
| SCHEMBL15547428 | 0.85 | HNF4A (0.39) | MAPTHPGDKDM4EMEN1KMT2A | |
| SCHEMBL15547430 | 0.85 | HNF4A (0.39) | MAPTHPGDKDM4EMEN1KMT2A | |
| SCHEMBL15545364 | 0.83 | CA12 (0.48) | MAPTHTTKDM4EMEN1KMT2A | |
| SCHEMBL14547388 | 0.78 | MAPT (0.45) | CSNK2A1MAPTHTTHPGDKDM4E | |
| SCHEMBL13575866 | 0.78 | MAPT (0.45) | CSNK2A1MAPTHTTHPGDKDM4E | |
| SCHEMBL6934974 | 0.76 | NPSR1 (0.43) | MAPTKDM4EMEN1KMT2ARAB9A | |
| SCHEMBL6934690 | 0.76 | MAPT (0.46) | MAPTHPGDKDM4EKMT2ARAB9A | |
| SCHEMBL6934845 | 0.76 | MAPT (0.46) | MAPTHPGDKDM4EKMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012098044-A1 | PROCESS FOR THE PREPARATION OF N,N-DIISOPROPYL-3-(2-HYDROXY-5-METHYLPHENYL)- 3-PHENYL PROPYLAMINE AND ITS SALTS STARTING FROM A NOVEL INTERMEDIATE | CAMBREX PROFARMACO MILANO S.R.L. (IT) | 2012-07-26 | — | — | WO | claimed |
| EP-2476665-A1 | Process for the preparation of N,N-diisopropyl-3-(2-hydroxy-5-methylphenyl)- 3-phenyl propylamine and its salts starting from a novel intermediate | Cambrex Profarmaco Milano S.r.l. (IT) | 2012-07-18 | — | — | EP | claimed |
| WO-2012098044-A1 | PROCESS FOR THE PREPARATION OF N,N-DIISOPROPYL-3-(2-HYDROXY-5-METHYLPHENYL)- 3-PHENYL PROPYLAMINE AND ITS SALTS STARTING FROM A NOVEL INTERMEDIATE | CAMBREX PROFARMACO MILANO S.R.L. (IT) | 2012-07-26 | — | — | WO | disclosed |
| WO-2012098044-A1 | PROCESS FOR THE PREPARATION OF N,N-DIISOPROPYL-3-(2-HYDROXY-5-METHYLPHENYL)- 3-PHENYL PROPYLAMINE AND ITS SALTS STARTING FROM A NOVEL INTERMEDIATE | CAMBREX PROFARMACO MILANO S.R.L. (IT) | 2012-07-26 | — | — | WO | disclosed |
| EP-2476665-A1 | Process for the preparation of N,N-diisopropyl-3-(2-hydroxy-5-methylphenyl)- 3-phenyl propylamine and its salts starting from a novel intermediate | Cambrex Profarmaco Milano S.r.l. (IT) | 2012-07-18 | — | — | EP | disclosed |
| EP-2476665-A1 | Process for the preparation of N,N-diisopropyl-3-(2-hydroxy-5-methylphenyl)- 3-phenyl propylamine and its salts starting from a novel intermediate | Cambrex Profarmaco Milano S.r.l. (IT) | 2012-07-18 | — | — | EP | disclosed |