Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HNF4A | P41235 | 1/20 | 0.39 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 2/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.36 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.36 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.36 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15547430 | 1.00 | HNF4A (0.39) | HNF4AACMSDLTB4RLTB4R2STAT3 | |
| SCHEMBL10316745 | 0.85 | CSNK2A1 (0.45) | LTB4RLTB4R2BCL2L1MCL1PTGS1 | |
| SCHEMBL10355817 | 0.85 | CSNK2A1 (0.45) | LTB4RLTB4R2BCL2L1MCL1PTGS1 | |
| SCHEMBL10316746 | 0.85 | CSNK2A1 (0.45) | LTB4RLTB4R2BCL2L1MCL1PTGS1 | |
| SCHEMBL15545364 | 0.79 | CA12 (0.48) | LTB4RLTB4R2KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL6934690 | 0.74 | MAPT (0.46) | LTB4RLTB4R2KDM4EMAPTHPGD | |
| SCHEMBL6934974 | 0.74 | NPSR1 (0.43) | LTB4RLTB4R2KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL6934845 | 0.74 | MAPT (0.46) | LTB4RLTB4R2KDM4EMAPTHPGD | |
| SCHEMBL27458727 | 0.72 | HNF4A (0.56) | HNF4AACMSDCNR2KLKB1CTSB | |
| SCHEMBL6937348 | 0.71 | SLC6A1 (0.44) | LTB4RLTB4R2SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014012832-A1 | PROCESS FOR THE PREPARATION OF 2-(3-N,N-DIISOPROPYLAMINO-1-PHENYLPROPYL)-4-HYDROXYMETHYL-PHENOL AND ITS DERIVATIVES | CAMBREX PROFARMACO MILANO S.R.L. (IT) | 2014-01-23 | — | — | WO | disclosed |