Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.42 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.42 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6934845 | 0.83 | MAPT (0.46) | LTB4RLTB4R2KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL6934690 | 0.83 | MAPT (0.46) | LTB4RLTB4R2KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL6937344 | 0.82 | SLC6A1 (0.44) | LTB4RLTB4R2SLC6A1POLBSMN1; SMN2 | |
| SCHEMBL6937348 | 0.82 | SLC6A1 (0.44) | LTB4RLTB4R2SLC6A1POLBSMN1; SMN2 | |
| SCHEMBL10355817 | 0.76 | CSNK2A1 (0.45) | NPSR1LTB4RLTB4R2MEN1KMT2A | |
| SCHEMBL10316746 | 0.76 | CSNK2A1 (0.45) | NPSR1LTB4RLTB4R2MEN1KMT2A | |
| SCHEMBL10316745 | 0.76 | CSNK2A1 (0.45) | NPSR1LTB4RLTB4R2MEN1KMT2A | |
| SCHEMBL17802368 | 0.75 | KMT2A (0.46) | MEN1KMT2ARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL15547428 | 0.74 | HNF4A (0.39) | LTB4RLTB4R2MEN1KMT2ARAB9A | |
| SCHEMBL15547430 | 0.74 | HNF4A (0.39) | LTB4RLTB4R2MEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019358-B1 | 3,3-DIARYLPROPYLAMINES , THEIR USE AND PREPARATION | PHARMACIA AB (SE) | 2003-05-07 | — | — | EP | disclosed |
| US-6313132-B1 | FOR THERAPY OF URINARY INCONTINENCE, ACETYLCHOLINE-MEDIATED DISORDER | PHARMACIA AB (SE) | 2001-11-06 | — | — | US | disclosed |
| EP-1019358-A1 | NOVEL COMPOUNDS, THEIR USE AND PREPARATION | Pharmacia & Upjohn AB (SE) | 2000-07-19 | — | — | EP | disclosed |
| WO-1998043942-A1 | NOVEL COMPOUNDS, THEIR USE AND PREPARATION | PHARMACIA & UPJOHN AB (SE) | 1998-10-08 | — | — | WO | disclosed |