Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.33 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.33 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 3/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 4/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13390674 | 0.95 | BRD9 (0.33) | ROCK1BRD9BAZ2BBAZ2ABRD4 | |
| SCHEMBL3300310 | 0.86 | BRD9 (0.33) | ROCK1BRD9BAZ2BBAZ2ABRD4 | |
| SCHEMBL13409590 | 0.85 | PKM (0.33) | IRAK4 | |
| SCHEMBL13391273 | 0.84 | F2 (0.34) | ROCK1F2KEAP1NFE2L2ALDH1A1 | |
| SCHEMBL13390456 | 0.83 | NR1H2 (0.32) | KEAP1NFE2L2 | |
| SCHEMBL10316932 | 0.83 | F2 (0.34) | F2KEAP1NFE2L2 | |
| SCHEMBL3302859 | 0.82 | KEAP1 (0.35) | ROCK1F2KEAP1NFE2L2ALDH1A1 | |
| SCHEMBL10317092 | 0.82 | IRAK4 (0.33) | BRD4F2KEAP1NFE2L2ALDH1A1 | |
| SCHEMBL3304036 | 0.82 | KEAP1 (0.41) | ROCK1KEAP1NFE2L2 | |
| SCHEMBL3297315 | 0.82 | KDM4C (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121600-B1 | SUBSTITUTED ARYLSULPHONYLGLYCINES, THE PREPARATION THEREOF AND THE USE THEREOF AS PHARMACEUTICAL COMPOSITIONS | BOEHRINGER INGELHEIM INT (DE) | 2012-07-18 | — | — | EP | disclosed |