Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK1 | P49759 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 6/20 | 0.42 |
| ▸ | WNT3A | P56704 | 6/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | PNMT | P11086 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | PRKCI | P41743 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PKLR | P30613 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3492241 | 0.89 | PRKCI (0.47) | DYRK1ADYRK1BDRD2DRD3PNMT | |
| SCHEMBL28324711 | 0.86 | RIPK1 (0.42) | CTNNB1WNT3ADRD2DRD3PNMT | |
| SCHEMBL4734542 | 0.82 | DYRK1A (0.43) | CLK1DYRK1ADYRK1BCTNNB1WNT3A | |
| SCHEMBL97687 | 0.82 | DYRK1A (0.47) | CLK1DYRK1ADYRK1BCTNNB1WNT3A | |
| SCHEMBL4849472 | 0.82 | DYRK1A (0.43) | CLK1DYRK1ADYRK1BCTNNB1WNT3A | |
| SCHEMBL4967364 | 0.77 | DRD2 (0.47) | DRD2DRD3PNMTKDM1A | |
| SCHEMBL4737647 | 0.77 | ACACB (0.42) | CLK1DYRK1ADYRK1BCTNNB1WNT3A | |
| SCHEMBL4599854 | 0.76 | DYRK1A (0.54) | DYRK1APRKCIGSK3BPKMPKLR | |
| SCHEMBL19538178 | 0.76 | DPP4 (0.42) | PKMPKLR | |
| SCHEMBL28482571 | 0.75 | PNMT (0.42) | DRD2DRD3PNMTKDM1AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114585360-A | Methods of using the same for the treatment of epilepsy | 特维娜有限公司 | 2022-06-03 | — | — | CN | disclosed |
| EP-3851436-A1 | NOVEL HETEROAROMATIC AMIDE DERIVATIVE AND MEDICINE CONTAINING SAME | Kaken Pharmaceutical Co., Ltd. (JP) | 2021-07-21 | — | — | EP | disclosed |
| CN-107922396-A | Colony stimulating factor-1 receptor (CSF-1R) inhibitors | 建新公司 | 2018-04-17 | — | — | CN | disclosed |
| EP-1937669-B9 | NOVEL BENZOPYRAN DERIVATIVES AS POTASSIUM CHANNEL OPENERS | JANSSEN PHARMACEUTICA NV (BE) | 2012-07-18 | — | — | EP | disclosed |
| US-4680411-A | Pyrano[2,3-g]indoles useful as anti-ulcerous, anti-inflammatory and antalgic agent | SOCIETE DE RECHERCHES INDUSTRIELLES (FR) | 1987-07-14 | — | — | US | disclosed |
| EP-0043752-B1 | PYRANOINDOLE DERIVATIVE AND PROCESS FOR ITS PREPARATION | SOCIETE DE RECHERCHES INDUSTRIELLES S.O.R.I. Société anonyme dite: (FR) | 1984-06-13 | — | — | EP | disclosed |
| US-4436915-A | ANTIULCER, ANTIINFLAMMATORY | SOCIETE DE RECHERCHES INDUSTRIELLES (FR) | 1984-03-13 | — | — | US | disclosed |
| EP-0043752-A1 | Pyranoindole derivative and process for its preparation | SOCIETE DE RECHERCHES INDUSTRIELLES S.O.R.I. Société anonyme dite: (FR) | 1982-01-13 | — | — | EP | disclosed |