Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 2/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 9/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 9/20 | 0.35 |
| ▸ | RXRA | P19793 | 5/20 | 0.35 |
| ▸ | RIPK2 | O43353 | 3/20 | 0.34 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.34 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | TNKS | O95271 | 3/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.34 |
| ▸ | SULT2A1 | Q06520 | 1/20 | 0.34 |
| ▸ | ATR | Q13535 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4168810 | 0.90 | GRM1 (0.41) | PTGS2XDHRIPK2 | |
| SCHEMBL4164283 | 0.83 | GRM1 (0.47) | PTGS2XDH | |
| SCHEMBL4161595 | 0.80 | TDP2 (0.42) | PTGS2XDH | |
| SCHEMBL4702957 | 0.79 | PTGS2 (0.39) | PTGS2RIPK2ATR | |
| SCHEMBL4165708 | 0.77 | GRM1 (0.42) | PTGS2XDHRIPK2 | |
| SCHEMBL4165879 | 0.76 | RIPK2 (0.40) | PTGS2XDHRIPK2KCNH2 | |
| SCHEMBL4173644 | 0.75 | GRM1 (0.41) | PTGS2XDHRIPK2 | |
| SCHEMBL4165895 | 0.75 | XDH (0.38) | XDH | |
| SCHEMBL4164801 | 0.74 | GRM1 (0.59) | — | |
| SCHEMBL4158635 | 0.74 | XDH (0.38) | XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1999132-B1 | AZOLOPYRIMIDINES AS INHIBITORS OF CANNABINOID 1 ACTIVITY | IRM LLC (BM) | 2012-07-18 | — | — | EP | disclosed |