Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | BCL2 | P10415 | 1/20 | 0.33 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | CDC25B | P30305 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8670423 | 0.81 | CA1 (0.40) | ALDH1A1HIF1AHSD17B10CYP1A2 | |
| SCHEMBL10323235 | 0.71 | BCL2 (0.41) | CALM1HTR2ABCL2BCL2L1HIF1A | |
| SCHEMBL1395580 | 0.70 | CALM1 (0.41) | APOBEC3AAPOBEC3GCALM1GPR55L3MBTL1 | |
| SCHEMBL2091627 | 0.70 | CALM1 (0.57) | CALM1BCL2BCL2L1 | |
| SCHEMBL10384790 | 0.69 | CALM1 (0.61) | CALM1HTR2ABCL2BCL2L1ALDH1A1 | |
| SCHEMBL4642432 | 0.69 | HTR2A (0.56) | APOBEC3AAPOBEC3GCALM1GPR55HTR2A | |
| SCHEMBL27848664 | 0.68 | CALM1 (0.42) | APOBEC3AAPOBEC3GCALM1BCL2BCL2L1 | |
| SCHEMBL10322337 | 0.68 | CALM1 (0.42) | CALM1HTR2ABCL2BCL2L1HIF1A | |
| SCHEMBL2301492 | 0.68 | KCNH2 (0.40) | — | |
| SCHEMBL2162367 | 0.67 | ALDH1A1 (0.32) | HTR2AL3MBTL1ALDH1A1HIF1ACYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811422-A | USEFUL FOR TREATING VIRAL INFECTIONS | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-09-22 | — | — | US | disclosed |
| US-5610294-A | VIRAL TREATMENT | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-03-11 | — | — | US | disclosed |