Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 10/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | PRKCI | P41743 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | G6PD | P11413 | 1/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2989381 | 0.86 | SLC6A4 (0.43) | SLC6A4HTR2APRKCIACHELMNA | |
| SCHEMBL1708813 | 0.83 | SLC6A4 (0.50) | SLC6A4HTR2APRKCIACHEKDM4E | |
| SCHEMBL10819198 | 0.82 | TAAR1 (0.56) | SLC6A4HTR2APRKCIACHETAAR1 | |
| SCHEMBL2176041 | 0.81 | ALDH1A1 (0.50) | SLC6A4HTR2APRKCIACHELMNA | |
| SCHEMBL29834174 | 0.79 | PRKCI (0.69) | SLC6A4HTR2APRKCIACHEKDM4E | |
| SCHEMBL4525352 | 0.79 | SLC6A4 (0.47) | SLC6A4HTR2APRKCIACHEKDM4E | |
| SCHEMBL4532794 | 0.79 | SLC6A4 (0.47) | SLC6A4HTR2APRKCIACHEKDM4E | |
| SCHEMBL1664066 | 0.79 | SLC6A4 (0.64) | SLC6A4HTR2APRKCIACHEKDM4E | |
| SCHEMBL3338265 | 0.79 | PRKCI (0.69) | SLC6A4HTR2APRKCIACHEKDM4E | |
| SCHEMBL30402664 | 0.79 | SLC6A4 (0.64) | SLC6A4HTR2APRKCIACHEKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117460732-A | Pyrrolopyridone compounds, preparation method and application thereof | 杭州中美华东制药有限公司 | 2024-01-26 | — | — | CN | disclosed |
| WO-2022258044-A1 | PYRROLOPYRIDINONE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 杭州中美华东制药有限公司 | 2022-12-15 | — | — | WO | disclosed |
| US-8748610-B2 | Compounds as TRPV1 antagonists, pharmaceutical compositions and medical uses thereof | FL THERAPEUTICS LLC (US) | 2014-06-10 | — | — | US | disclosed |
| US-8748610-B2 | Compounds as TRPV1 antagonists, pharmaceutical compositions and medical uses thereof | FL THERAPEUTICS LLC (US) | 2014-06-10 | — | — | US | disclosed |
| US-8748610-B2 | Compounds as TRPV1 antagonists, pharmaceutical compositions and medical uses thereof | FL THERAPEUTICS LLC (US) | 2014-06-10 | — | — | US | disclosed |
| US-20120184509-A1 | Compounds as TRVP1 Blockers, Pharmaceutical Compositions and Medical Uses Thereof | ZHUHAI BEIHAI BIOTECH CO., LTD. (CN) | 2012-07-19 | — | — | US | disclosed |
| US-20120184509-A1 | Compounds as TRVP1 Blockers, Pharmaceutical Compositions and Medical Uses Thereof | ZHUHAI BEIHAI BIOTECH CO., LTD. (CN) | 2012-07-19 | — | — | US | disclosed |
| US-20120184509-A1 | Compounds as TRVP1 Blockers, Pharmaceutical Compositions and Medical Uses Thereof | ZHUHAI BEIHAI BIOTECH CO., LTD. (CN) | 2012-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120184509-A1 | Compounds as TRVP1 Blockers, Pharmaceutical Compositions and Medical Uses Thereof | TRPV1, TRPV4, TRPV3 | SLC6A4 237/4885HTR2A 306/4885PRKCI 3693/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.