Known targets — ChEMBL curated mechanism
KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2
The experimentally established mechanism targets of Guanidine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL930972 | 0.91 | KDM4E (0.31) | — | |
| Ammonia Solution, Strong SCHEMBL932033 | 0.90 | — | — | |
| Guanidine SCHEMBL13835198 | 0.80 | GPR84 (0.33) | — | |
| SCHEMBL931567 | 0.80 | CHRM2 (0.30) | — | |
| SCHEMBL887329 | 0.72 | KDM4E (0.34) | — | |
| SCHEMBL11336478 | 0.71 | KDM4E (0.31) | — | |
| SCHEMBL10324737 | 0.70 | ALDH1A1 (0.34) | — | |
| SCHEMBL29519147 | 0.69 | GPR84 (0.35) | — | |
| SCHEMBL2436265 | 0.69 | GPR84 (0.35) | — | |
| SCHEMBL931274 | 0.69 | KDM4E (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120184635-A1 | Flameproof expandable polymerizates | Sunpor Kunststoff Ges m.b.H. (AT) | 2012-07-19 | — | — | US | disclosed |