SCHEMBL10324737

SCHEMBL10324737

Nc1cccc2c1P(O)(=S)Oc1ccccc1-2

nearest known ligand 0.34

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
HSD17B10 Q99714 1/20 0.31
KDM4E B2RXH2 1/20 0.30
MAPK1 P28482 1/20 0.30
ATM Q13315 1/20 0.30
PTPRC P08575 1/20 0.30
ADORA2A P29274 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13278323 0.80 ALDH1A1 (0.34) ALDH1A1L3MBTL1HSD17B10KDM4EMAPK1
SCHEMBL10324852 0.77 HTR3E (0.37)
SCHEMBL930972 0.73 KDM4E (0.31) KDM4EMAPK1ATM
SCHEMBL887329 0.72 KDM4E (0.34) KDM4EMAPK1ATM
Ammonia Solution, Strong SCHEMBL932033 0.72
Guanidine SCHEMBL10324850 0.70
SCHEMBL18076604 0.65 KDM4E (0.36) KDM4EMAPK1ATM
SCHEMBL30426151 0.64 GPR84 (0.52) KDM4EMAPK1ATM
SCHEMBL14901026 0.64 KDM4E (0.34) KDM4EMAPK1ATM
SCHEMBL887277 0.64 GPR84 (0.52) KDM4EMAPK1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120184635-A1 Flameproof expandable polymerizates Sunpor Kunststoff Ges m.b.H. (AT) 2012-07-19 US disclosed
CN-102597091-A Flame retardant expandable polymers SUNPOR KUNSTSTOFF GMBH 2012-07-18 CN disclosed