SCHEMBL10324974

SCHEMBL10324974

[c]1ccccc1-c1cccc2c1sc1ccccc12

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.48
PARP14 Q460N5 1/20 0.44
GPR3 P46089 1/20 0.42
PRKDC P78527 7/20 0.37
PIK3CD O00329 2/20 0.36
PIK3CB P42338 2/20 0.36
BRD4 O60885 1/20 0.36
PIK3CA P42336 1/20 0.36
MTOR P42345 1/20 0.36
PIK3CG P48736 1/20 0.36
KCNH2 Q12809 1/20 0.36
BRDT Q58F21 1/20 0.36
MAPT P10636 3/20 0.34
RAB9A P51151 2/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TNKS O95271 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15525024 0.85 ALOX5 (0.55) ALOX5PARP14GPR3PRKDCPIK3CD
SCHEMBL23088986 0.81 ALOX5 (0.57) ALOX5PARP14GPR3PRKDCPIK3CD
SCHEMBL2592095 0.80 GPR3 (0.42) ALOX5PARP14GPR3BRDTMAPT
SCHEMBL16553319 0.80 ALOX5 (0.61) ALOX5PARP14GPR3PRKDCPIK3CD
SCHEMBL12996528 0.78 ALOX5 (0.59) ALOX5PARP14GPR3PRKDCPIK3CD
SCHEMBL431845 0.78 ALOX5 (0.59) ALOX5PARP14GPR3PRKDCPIK3CD
SCHEMBL10018846 0.78 ALOX5 (0.59) ALOX5PARP14GPR3PRKDCPIK3CD
SCHEMBL429382 0.78 ALOX5 (0.59) ALOX5PARP14GPR3PRKDCPIK3CD
SCHEMBL15987505 0.75 ALOX5 (0.56) ALOX5PARP14GPR3PRKDCPIK3CD
SCHEMBL9890847 0.74 ALOX5 (0.56) ALOX5PARP14GPR3PRKDCPIK3CD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2462124-B9 MESOIONIC PESTICIDES DU PONT (US) 2017-08-23 EP claimed
US-20160066577-A1 MESOIONIC PESTICIDES FMC CORPORATION 2016-03-10 US claimed
US-20140206536-A1 MESOIONIC PESTICIDES E I DU PONT DE NEMOURS AND COMPANY (US) 2014-07-24 US claimed
US-8722690-B2 Mesoionic pesticides E I DU PONT DE NEMOURS AND COMPANY (US) 2014-05-13 US claimed
US-20120277100-A1 MESOIONIC PESTICIDES FMC CORPORATION 2012-11-01 US claimed
CN-110896635-B Organic compound, light-emitting element, light-emitting device, electronic device, and lighting device 株式会社半导体能源研究所 2023-11-03 CN disclosed
CN-116568685-A Organic compound, carrier transporting material, host material, light-emitting device, electronic apparatus, and lighting device 株式会社半导体能源研究所 2023-08-08 CN disclosed
CN-116456742-A Light emitting element, display device, electronic device, and lighting device 株式会社半导体能源研究所 2023-07-18 CN disclosed
CN-116056479-A Light-emitting element 株式会社半导体能源研究所 2023-05-02 CN disclosed
CN-111048679-B Light-emitting element 株式会社半导体能源研究所 2023-04-07 CN disclosed
US-11573488-B2 Composition for holographic recording medium, and holographic recording medium MITSUBISHI CHEMICAL CORPORATION (JP) 2023-02-07 US disclosed
CN-115394944-A Light-emitting element, light-emitting device, electronic device, lighting device, and novel organic compound 株式会社半导体能源研究所 2022-11-25 CN disclosed
US-20160066577-A1 MESOIONIC PESTICIDES FMC CORPORATION 2016-03-10 US disclosed
US-9210932-B2 Mesoionic pesticides E I DU PONT DE NEMOURS AND COMPANY (US) 2015-12-15 US disclosed
US-20140206536-A1 MESOIONIC PESTICIDES E I DU PONT DE NEMOURS AND COMPANY (US) 2014-07-24 US disclosed
US-8722690-B2 Mesoionic pesticides E I DU PONT DE NEMOURS AND COMPANY (US) 2014-05-13 US disclosed
EP-2462124-B1 MESOIONIC PESTICIDES DU PONT (US) 2014-01-08 EP disclosed
EP-2617712-A1 NITROGEN-CONTAINING AROMATIC HETEROCYCLIC DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING SAME Idemitsu Kosan Co., Ltd. (JP) 2013-07-24 EP disclosed
US-20120277100-A1 MESOIONIC PESTICIDES FMC CORPORATION 2012-11-01 US disclosed
US-20120181524-A1 NITROGEN-CONTAINING AROMATIC HETEROCYCLIC DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-07-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120181524-A1 NITROGEN-CONTAINING AROMATIC HETEROCYCLIC DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME AOC3, NPR3, NR0B1 ALOX5 3465/4885PARP14 3717/4885GPR3 281/4885
US-20140206536-A1 MESOIONIC PESTICIDES CHRM3, CHRM2, CHRM5 ALOX5 2481/4885PARP14 4777/4885GPR3 105/4885
US-20160066577-A1 MESOIONIC PESTICIDES CHRM3, CHRM2, CHRM5 ALOX5 2481/4885PARP14 4777/4885GPR3 105/4885
US-20120277100-A1 MESOIONIC PESTICIDES CHRM3, CHRM2, CHRM5 ALOX5 2475/4885PARP14 4781/4885GPR3 110/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.