Penoxsulam

Penoxsulam

SCHEMBL10325449

COc1cnc(OC)n2nc(NS(=O)(=O)c3c(OCC(F)F)cccc3C(F)(F)F)nc12.O=C(O)COc1nc(Cl)c(Cl)cc1Cl

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PTK2 Q05397 7/20 0.33
LRRK2 Q5S007 2/20 0.32
EGFR P00533 2/20 0.31
SCN9A Q15858 2/20 0.31
CCR4 P51679 1/20 0.31
PSEN1 P49768 1/20 0.31
PSEN2 P49810 1/20 0.31
KCNH2 Q12809 1/20 0.31
APH1B Q8WW43 1/20 0.31
NCSTN Q92542 1/20 0.31
APH1A Q96BI3 1/20 0.31
PSENEN Q9NZ42 1/20 0.31
PI4KB Q9UBF8 1/20 0.31
HCRTR1 O43613 1/20 0.31
HCRTR2 O43614 1/20 0.31
PTGES O14684 1/20 0.30
ALK Q9UM73 1/20 0.30
MAPK10 P53779 1/20 0.30
TRPV1 Q8NER1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Penoxsulam SCHEMBL20723729 0.94 PTK2 (0.33) PTK2EGFR
Penoxsulam SCHEMBL20723816 0.94 PTK2 (0.30) PTK2
Penoxsulam SCHEMBL20723726 0.92
Penoxsulam SCHEMBL20723833 0.87 CCR4 (0.32) CCR4
Penoxsulam SCHEMBL116968 0.86 PSEN1 (0.35) EGFRSCN9ACCR4PSEN1PSEN2
Penoxsulam SCHEMBL22587372 0.85 PSEN1 (0.34) PTK2EGFRSCN9ACCR4PSEN1
Penoxsulam SCHEMBL2430920 0.85 PKM (0.37) PTGES
Penoxsulam SCHEMBL20723756 0.84 PTK2 (0.33) PTK2EGFRCCR4PTGESMAPK10
Penoxsulam SCHEMBL20723714 0.83 SLC40A1 (0.33) PTK2PSEN1PSEN2KCNH2APH1B
Penoxsulam SCHEMBL12472642 0.83 PDCD1 (0.31) PTK2HCRTR1HCRTR2MAPK10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120184437-A1 SYNERGISTIC HERBICIDAL COMPOSITION CONTAINING PENOXSULAM, TRICLOPYR AND IMAZETHAPYR DOW AGROSCIENCES LLC (US) 2012-07-19 US claimed
US-20240008481-A1 METHOD FOR CONTROLLING UNDESIRABLE VEGETATION IN AN AQUATIC ENVIRONMENT BASF Agro B.V. (NL) 2024-01-11 US disclosed
US-9968084-B2 Synergistic herbicidal composition containing penoxsulam, triclopyr and imazethapyr DOW AGROSCIENCES LLC (US) 2018-05-15 US disclosed
US-20160353738-A1 SYNERGISTIC HERBICIDAL COMPOSITION CONTAINING PENOXSULAM, TRICLOPYR AND BISPYRIBAC DOW AGROSCIENCES LLC (US) 2016-12-08 US disclosed
US-20160165891-A1 SYNERGISTIC HERBICIDAL COMPOSITION CONTAINING PENOXSULAM, TRICLOPYR AND BISPYRIBAC DOW AGROSCIENCES LLC (US) 2016-06-16 US disclosed
US-20120184437-A1 SYNERGISTIC HERBICIDAL COMPOSITION CONTAINING PENOXSULAM, TRICLOPYR AND IMAZETHAPYR DOW AGROSCIENCES LLC (US) 2012-07-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240008481-A1 METHOD FOR CONTROLLING UNDESIRABLE VEGETATION IN AN AQUATIC ENVIRONMENT ATP5PO, GUSB, WFS1 PTK2 4128/4885LRRK2 2905/4885EGFR 4573/4885
US-20160353738-A1 SYNERGISTIC HERBICIDAL COMPOSITION CONTAINING PENOXSULAM, TRICLOPYR AND BISPYRIBAC PARG, PKM, PARN PTK2 2855/4885LRRK2 2587/4885EGFR 4314/4885
US-20160165891-A1 SYNERGISTIC HERBICIDAL COMPOSITION CONTAINING PENOXSULAM, TRICLOPYR AND BISPYRIBAC PARG, PKM, IPMK PTK2 2847/4885LRRK2 2968/4885EGFR 4069/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.