Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 16/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.62 |
| ▸ | SOAT1 | P35610 | 3/20 | 0.62 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.53 |
| ▸ | MGLL | Q99685 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31605471 | 0.84 | HPGD (0.61) | MGLLCYP2C9HPGDSMN1; SMN2 | |
| SCHEMBL10326124 | 0.81 | DGAT1 (0.68) | DGAT1KCNH2SOAT1ADORA2ACYP3A4 | |
| SCHEMBL10380785 | 0.81 | DGAT1 (0.73) | DGAT1KCNH2SOAT1ADORA2ACYP3A4 | |
| SCHEMBL4566517 | 0.79 | DGAT1 (0.60) | DGAT1KCNH2SOAT1ADORA2ACYP3A4 | |
| SCHEMBL15230954 | 0.79 | DGAT1 (0.57) | DGAT1KCNH2SOAT1ADORA2APRMT5 | |
| SCHEMBL17038781 | 0.78 | SMN1; SMN2 (0.74) | CYP2C9HPGDSMN1; SMN2 | |
| SCHEMBL29564805 | 0.78 | SMN1; SMN2 (0.74) | CYP2C9HPGDSMN1; SMN2 | |
| SCHEMBL10381569 | 0.78 | DGAT1 (0.62) | DGAT1KCNH2SOAT1ADORA2ACYP3A4 | |
| SCHEMBL6994210 | 0.77 | DGAT1 (0.54) | DGAT1KCNH2SOAT1ADORA2ACYP3A4 | |
| SCHEMBL4560514 | 0.77 | DGAT1 (0.62) | DGAT1KCNH2SOAT1ADORA2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012096813-A1 | IMIDAZOLE DERIVATIVES | MERCK SHARP & DOHME CORP. (US) | 2012-07-19 | — | — | WO | disclosed |