Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 16/20 | 0.68 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.68 |
| ▸ | SOAT1 | P35610 | 4/20 | 0.68 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.53 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4560514 | 0.96 | DGAT1 (0.62) | DGAT1KCNH2SOAT1PRMT5ADORA2A | |
| SCHEMBL10381569 | 0.84 | DGAT1 (0.62) | DGAT1KCNH2SOAT1ADORA2ACYP3A4 | |
| SCHEMBL10380785 | 0.84 | DGAT1 (0.73) | DGAT1KCNH2SOAT1ADORA2ACYP3A4 | |
| SCHEMBL4561861 | 0.82 | DGAT1 (0.65) | DGAT1KCNH2SOAT1ADORA2ACYP3A4 | |
| SCHEMBL1742865 | 0.82 | GPR119 (0.57) | DGAT1KCNH2SOAT1PRMT5 | |
| SCHEMBL10325481 | 0.81 | DGAT1 (0.62) | DGAT1KCNH2SOAT1PRMT5ADORA2A | |
| SCHEMBL19175769 | 0.81 | DGAT1 (0.77) | DGAT1KCNH2SOAT1ADORA2ACYP3A4 | |
| SCHEMBL4566517 | 0.80 | DGAT1 (0.60) | DGAT1KCNH2SOAT1ADORA2ACYP3A4 | |
| SCHEMBL6995535 | 0.80 | DGAT1 (0.61) | DGAT1KCNH2SOAT1ADORA2ACYP3A4 | |
| SCHEMBL1687841 | 0.79 | HTR3E (0.54) | DGAT1KCNH2SOAT1ADORA2ACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012096813-A1 | IMIDAZOLE DERIVATIVES | MERCK SHARP & DOHME CORP. (US) | 2012-07-19 | — | — | WO | disclosed |