Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.34 |
| ▸ | PGD | P52209 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | PGK1 | P00558 | 1/20 | 0.30 |
| ▸ | PGK2 | P07205 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7170688 | 0.91 | PDE4A (0.52) | ALDH1A1PDE4ALMNAUSP2SLCO1B1 | |
| SCHEMBL1403805 | 0.91 | PDE4A (0.52) | ALDH1A1PDE4ALMNAUSP2SLCO1B1 | |
| SCHEMBL3810811 | 0.91 | PDE4A (0.52) | ALDH1A1PDE4ALMNAUSP2SLCO1B1 | |
| SCHEMBL1892966 | 0.89 | PDE4A (0.50) | ALDH1A1PDE4ALMNAUSP2SLCO1B1 | |
| SCHEMBL5073736 | 0.87 | PDE4A (0.48) | ALDH1A1PDE4ALMNAUSP2SLCO1B1 | |
| SCHEMBL5139535 | 0.85 | PDE4A (0.46) | ALDH1A1PDE4ALMNAUSP2SLCO1B1 | |
| SCHEMBL419463 | 0.85 | MPI (0.37) | ALDH1A1 | |
| SCHEMBL624112 | 0.85 | MPI (0.37) | ALDH1A1 | |
| SCHEMBL2123186 | 0.84 | PDE4A (0.45) | ALDH1A1PDE4ALMNAUSP2SLCO1B1 | |
| Bicarbonate SCHEMBL8384988 | 0.83 | MPI (0.36) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904489-B1 | PROCESS FOR THE SYNTHESIS OF TRIAZOLES | RIB X PHARMACEUTICALS INC (US) | 2011-01-26 | — | — | EP | claimed |