Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.31 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1403805 | 0.96 | PDE4A (0.52) | PDE4ALMNAL3MBTL1USP2SLCO1B1 | |
| SCHEMBL7170688 | 0.96 | PDE4A (0.52) | PDE4ALMNAL3MBTL1USP2SLCO1B1 | |
| SCHEMBL3810811 | 0.96 | PDE4A (0.52) | PDE4ALMNAL3MBTL1USP2SLCO1B1 | |
| SCHEMBL1892966 | 0.94 | PDE4A (0.50) | PDE4ALMNAL3MBTL1USP2SLCO1B1 | |
| SCHEMBL5139535 | 0.91 | PDE4A (0.46) | PDE4ALMNAL3MBTL1USP2SLCO1B1 | |
| SCHEMBL2123186 | 0.89 | PDE4A (0.45) | PDE4ALMNAL3MBTL1USP2SLCO1B1 | |
| SCHEMBL1032576 | 0.87 | ALDH1A1 (0.40) | PDE4ALMNAL3MBTL1USP2SLCO1B1 | |
| SCHEMBL16894036 | 0.82 | ALDH1A1 (0.42) | PDE4ALMNAL3MBTL1USP2SLCO1B1 | |
| SCHEMBL23414176 | 0.80 | PDE4A (0.45) | PDE4ALMNAL3MBTL1USP2SLCO1B1 | |
| SCHEMBL23414148 | 0.80 | PDE4A (0.45) | PDE4ALMNAL3MBTL1USP2SLCO1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6645535-B2 | Gastrointestinal disorders | WM. WRIGLEY JR. COMPANY | 2003-11-11 | — | — | US | claimed |
| WO-2002051259-A1 | COATED CHEWING GUM PRODUCTS CONTAINING VARIOUS ANTACIDS | WM. WRIGLEY JR. COMPANY (US) | 2002-07-04 | — | — | WO | claimed |
| US-20010021403-A1 | Coated chewing gum products containing various antacids | WM. WRIGLEY JR. COMPANY | 2001-09-13 | — | — | US | claimed |
| US-20080153880-A1 | PAN-ALPHA-2 RECEPTOR AGONIST AND ACID REDUCER COMPOSITIONS FOR TREATING GASTROINTESTINAL MOTILITY DISORDERS | ALLERGAN, INC. | 2008-06-26 | — | — | US | disclosed |
| US-20080153881-A1 | ALPHA-2B RECEPTOR AGONIST AND ACID REDUCER COMPOSITIONS FOR TREATING GASTROINTESTINAL MOTILITY DISORDERS | ALLERGAN, INC. | 2008-06-26 | — | — | US | disclosed |
| US-20070239104-A1 | Anti acid G/tube pad | FEERRAR ANGELA C | 2007-10-11 | — | — | US | disclosed |
| US-6645535-B2 | Gastrointestinal disorders | WM. WRIGLEY JR. COMPANY | 2003-11-11 | — | — | US | disclosed |
| WO-2002051259-A1 | COATED CHEWING GUM PRODUCTS CONTAINING VARIOUS ANTACIDS | WM. WRIGLEY JR. COMPANY (US) | 2002-07-04 | — | — | WO | disclosed |
| US-20010021403-A1 | Coated chewing gum products containing various antacids | WM. WRIGLEY JR. COMPANY | 2001-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080153880-A1 | PAN-ALPHA-2 RECEPTOR AGONIST AND ACID REDUCER COMPOSITIONS FOR TREATING GASTROINTESTINAL MOTILITY DISORDERS | MLNR, GIPR, FFAR2 | PDE4A 385/4885LMNA 4032/4885L3MBTL1 4752/4885 |
| US-20080153881-A1 | ALPHA-2B RECEPTOR AGONIST AND ACID REDUCER COMPOSITIONS FOR TREATING GASTROINTESTINAL MOTILITY DISORDERS | ADRA2B, GPBAR1, MLNR | PDE4A 260/4885LMNA 3459/4885L3MBTL1 4742/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.