Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL624112 | 1.00 | MPI (0.37) | MPIALDH1A1 | |
| Bicarbonate SCHEMBL8384988 | 0.98 | MPI (0.36) | MPIALDH1A1 | |
| Bicarbonate SCHEMBL8384375 | 0.98 | MPI (0.36) | MPIALDH1A1 | |
| SCHEMBL1607595 | 0.94 | MPI (0.38) | MPIALDH1A1 | |
| SCHEMBL1032576 | 0.85 | ALDH1A1 (0.40) | ALDH1A1 | |
| SCHEMBL789905 | 0.82 | MPI (0.36) | MPI | |
| SCHEMBL426315 | 0.82 | MPI (0.36) | MPIALDH1A1 | |
| SCHEMBL2884877 | 0.82 | MPI (0.36) | MPIALDH1A1 | |
| SCHEMBL2354360 | 0.82 | MPI (0.36) | MPI | |
| SCHEMBL215097 | 0.82 | MPI (0.36) | MPIALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11931497-B2 | System and method for preparing peritoneal dialysis fluid at the time of use | BAXTER INTERNATIONAL INC. (US) | 2024-03-19 | — | — | US | disclosed |
| US-20230202973-A1 | BARNESIN A, DERIVATIVES AND USES THEREOF | LEIBNIZ-INSTITUT FÜR NATURSTOFF-FORSCHUNG UND INFEKTIONSBIOLOGIE E.V. (HKI) (DE) | 2023-06-29 | — | — | US | disclosed |
| US-20220211926-A1 | SYSTEM AND METHOD FOR PREPARING PERITONEAL DIALYSIS FLUID AT THE TIME OF USE | VANTIVE US HEALTHCARE LLC | 2022-07-07 | — | — | US | disclosed |
| US-11311657-B2 | Dialysis system for mixing treatment fluid at time of use | BAXTER INTERNATIONAL INC. (US) | 2022-04-26 | — | — | US | disclosed |
| EP-3762360-A1 | BARNESIN A, DERIVATIVES AND USES THEREOF | Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie (DE) | 2021-01-13 | — | — | EP | disclosed |
| US-20200231562-A1 | NOVEL MACROLIDE ANTIBIOTICS | LEIBNIZ-INSTITUT FÜR NATURSTOFF-FORSCHUNG UND INFEKTIONSBIOLOGIE E.V. (HKI) (DE) | 2020-07-23 | — | — | US | disclosed |
| US-10472326-B2 | PQSR modulators | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2019-11-12 | — | — | US | disclosed |
| US-20190298906-A1 | DIALYSIS SYSTEM FOR MIXING TREATMENT FLUID AT TIME OF USE | VANTIVE US HEALTHCARE LLC | 2019-10-03 | — | — | US | disclosed |
| WO-2019170705-A1 | BARNESIN A, DERIVATIVES AND USES THEREOF | LEIBNIZ-INSTITUT FÜR NATURSTOFF-FORSCHUNG UND INFEKTIONSBIOLOGIE E.V. - HANS-KNÖLL-INSTITUT - (DE) | 2019-09-12 | — | — | WO | disclosed |
| EP-3536684-A1 | BARNESIN A, DERIVATIVES AND USES THEREOF | Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie (DE) | 2019-09-11 | — | — | EP | disclosed |
| EP-0619704-A4 | METHOD AND COMPOSITION FOR TREATING TUMORS HAVING HIGH TYROSINASE ACTIVITY. | RUBIN DAVID (US) | 1997-03-26 | — | — | EP | disclosed |
| US-5420107-A | Fluids, inorganic lactic acid salts and administering | BROOKS, GEORGE A. | 1995-05-30 | — | — | US | disclosed |
| EP-0619704-A1 | METHOD AND COMPOSITION FOR TREATING TUMORS HAVING HIGH TYROSINASE ACTIVITY | Rubin, David (US) | 1994-10-19 | — | — | EP | disclosed |
| US-5340803-A | Method and compositions for treating tumors having high tyrosinase activity | CO ENZYME TECHNOLOGY LTD. (US) | 1994-08-23 | — | — | US | disclosed |
| US-5240914-A | Method and compositions for inhibiting tumor cell metabolism | Schwimmer, Adolph (US) | 1993-08-31 | — | — | US | disclosed |
| WO-1993008688-A1 | METHOD AND COMPOSITION FOR TREATING TUMORS HAVING HIGH TYROSINASE ACTIVITY | SCHWIMMER, ADOLPH (US) | 1993-05-13 | — | — | WO | disclosed |
| US-4584368-A | β-Glucuronidase activity and/or pH-dependent pharmaceuticals and thier methods of production | Schwimmer, Adolf W. (IL) | 1986-04-22 | — | — | US | disclosed |
| US-4337760-A | Method for the treatment of tumors with β-glucuronidase activity dependent pharmaceuticals | Schwimmer, Adolf (IL) | 1982-07-06 | — | — | US | disclosed |
| US-4327074-A | Method for diagnosis and selective treatment of infections of bacteria having β-glucuronidase activity | Schwimmer, Adolf W. | 1982-04-27 | — | — | US | disclosed |
| WO-1980000791-A1 | B-GLUCURONIDASE ACTIVITY AND/OR PH-DEPENDENT PHARMACEUTICALS AND THEIR METHODS OF PRODUCTION AND USE FOR SELECTIVE TREATMENT OF DISEASES | SCHWIMMER A (US) | 1980-05-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200231562-A1 | NOVEL MACROLIDE ANTIBIOTICS | MRPL21, MRPS18A, LSS | MPI 1066/4885ALDH1A1 4483/4885 |
| US-20230202973-A1 | BARNESIN A, DERIVATIVES AND USES THEREOF | SERPINB1, SERPINA3, CMA1 | MPI 1788/4885ALDH1A1 960/4885 |
| US-10472326-B2 | PQSR modulators | QARS1, SRPRA, MRPS35 | MPI 1289/4885ALDH1A1 4707/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.