Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL419463 | 1.00 | MPI (0.37) | MPIALDH1A1 | |
| Bicarbonate SCHEMBL8384988 | 0.98 | MPI (0.36) | MPIALDH1A1 | |
| Bicarbonate SCHEMBL8384375 | 0.98 | MPI (0.36) | MPIALDH1A1 | |
| SCHEMBL1607595 | 0.94 | MPI (0.38) | MPIALDH1A1 | |
| SCHEMBL1032576 | 0.85 | ALDH1A1 (0.40) | ALDH1A1 | |
| SCHEMBL789905 | 0.82 | MPI (0.36) | MPI | |
| SCHEMBL426315 | 0.82 | MPI (0.36) | MPIALDH1A1 | |
| SCHEMBL2884877 | 0.82 | MPI (0.36) | MPIALDH1A1 | |
| SCHEMBL2354360 | 0.82 | MPI (0.36) | MPI | |
| SCHEMBL215097 | 0.82 | MPI (0.36) | MPIALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230202973-A1 | BARNESIN A, DERIVATIVES AND USES THEREOF | LEIBNIZ-INSTITUT FÜR NATURSTOFF-FORSCHUNG UND INFEKTIONSBIOLOGIE E.V. (HKI) (DE) | 2023-06-29 | — | — | US | disclosed |
| EP-3762360-A1 | BARNESIN A, DERIVATIVES AND USES THEREOF | Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie (DE) | 2021-01-13 | — | — | EP | disclosed |
| US-20200231562-A1 | NOVEL MACROLIDE ANTIBIOTICS | LEIBNIZ-INSTITUT FÜR NATURSTOFF-FORSCHUNG UND INFEKTIONSBIOLOGIE E.V. (HKI) (DE) | 2020-07-23 | — | — | US | disclosed |
| US-10472326-B2 | PQSR modulators | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2019-11-12 | — | — | US | disclosed |
| WO-2019170705-A1 | BARNESIN A, DERIVATIVES AND USES THEREOF | LEIBNIZ-INSTITUT FÜR NATURSTOFF-FORSCHUNG UND INFEKTIONSBIOLOGIE E.V. - HANS-KNÖLL-INSTITUT - (DE) | 2019-09-12 | — | — | WO | disclosed |
| EP-3536684-A1 | BARNESIN A, DERIVATIVES AND USES THEREOF | Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie (DE) | 2019-09-11 | — | — | EP | disclosed |
| EP-3129385-B1 | NEOSORAPHENS AND THEIR USE IN THE TREATMENT OR PREVENTION OF A VIRAL INFECTION OR OF A TH17-ASSOCIATED INFLAMMATORY AND/OR AUTOIMMUNE DISEASE | HELMHOLTZ ZENTRUM INFEKTIONSFORSCHUNG GMBH (DE) | 2018-06-06 | — | — | EP | disclosed |
| EP-3166934-B1 | NOVEL MACROLIDE ANTIBIOTICS | HELMHOLTZ ZENTRUM INFEKTIONSFORSCHUNG GMBH (DE) | 2018-05-23 | — | — | EP | disclosed |
| US-9695461-B2 | Method for adapting a hydrolytic enzyme to a component that stabilizes the hydrolytic enzyme | HENKEL AG & CO. KGAA (DE) | 2017-07-04 | — | — | US | disclosed |
| EP-3166934-A1 | NOVEL MACROLIDE ANTIBIOTICS | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2017-05-17 | — | — | EP | disclosed |
| WO-2016005049-A1 | NOVEL MACROLIDE ANTIBIOTICS | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2016-01-14 | — | — | WO | disclosed |
| WO-2015154883-A1 | NEOSORAPHENS | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2015-10-15 | — | — | WO | disclosed |
| WO-2015113761-A1 | CLOSTRUBINS | Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e.V. (DE) | 2015-08-06 | — | — | WO | disclosed |
| EP-2756064-A2 | METHOD FOR ADAPTING A HYDROLYTIC ENZYME TO A COMPONENT THAT STABILIZES THE HYDROLYTIC ENZYME | Henkel AG & Co. KGaA (DE) | 2014-07-23 | — | — | EP | disclosed |
| US-20140186868-A1 | METHOD FOR ADAPTING A HYDROLYTIC ENZYME TO A COMPONENT THAT STABILIZES THE HYDROLYTIC ENZYME | HENKEL AG & CO., KGAA (DE) | 2014-07-03 | — | — | US | disclosed |
| US-8592359-B2 | Stabilized liquid enzyme-containing surfactant preparation comprising a monosaccharide glycerate | HENKEL AG & CO. KGAA (DE) | 2013-11-26 | — | — | US | disclosed |
| US-20130143787-A1 | STABILIZED LIQUID ENZYME-CONTAINING SURFACTANT PREPARATION | HENKEL AG & CO. KGAA (DE) | 2013-06-06 | — | — | US | disclosed |
| EP-2598625-A2 | STABILIZED LIQUID ENZYME-CONTAINING SURFACTANT PREPARATION | Henkel AG & Co. KGaA (DE) | 2013-06-05 | — | — | EP | disclosed |
| WO-2013037609-A2 | METHOD FOR ADAPTING A HYDROLYTIC ENZYME TO A COMPONENT THAT STABILIZES THE HYDROLYTIC ENZYME | HENKEL AG & CO. KGAA (DE) | 2013-03-21 | — | — | WO | disclosed |
| WO-2012019844-A2 | STABILIZED LIQUID ENZYME-CONTAINING SURFACTANT PREPARATION | HENKEL AG & CO. KGAA (DE) | 2012-02-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200231562-A1 | NOVEL MACROLIDE ANTIBIOTICS | MRPL21, MRPS18A, LSS | MPI 1066/4885ALDH1A1 4483/4885 |
| US-20230202973-A1 | BARNESIN A, DERIVATIVES AND USES THEREOF | SERPINB1, SERPINA3, CMA1 | MPI 1788/4885ALDH1A1 960/4885 |
| US-10472326-B2 | PQSR modulators | QARS1, SRPRA, MRPS35 | MPI 1289/4885ALDH1A1 4707/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.