Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10988177 | 0.78 | MGAM (0.41) | CTSKCTSLCTSB | |
| SCHEMBL3500237 | 0.77 | — | — | |
| SCHEMBL23732399 | 0.75 | — | — | |
| SCHEMBL6358498 | 0.75 | CTSK (0.36) | CTSKCTSLCTSB | |
| SCHEMBL28952300 | 0.75 | — | — | |
| SCHEMBL21813953 | 0.72 | CTSK (0.41) | CTSKCTSLCTSB | |
| SCHEMBL9853240 | 0.71 | — | — | |
| SCHEMBL28321992 | 0.71 | TSHR (0.42) | CTSK | |
| SCHEMBL4906996 | 0.71 | TSHR (0.42) | CTSK | |
| Bicarbonate SCHEMBL1597542 | 0.68 | SLC1A3 (0.34) | CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3207930-A1 | SUBSTITUTED BENZOAZEPINES AS TOLL-LIKE RECEPTOR MODULATORS | VentiRx Pharmaceuticals, Inc. (US) | 2017-08-23 | — | — | EP | disclosed |
| CN-106518851-A | Substituted benzoazepines as toll-like receptor modulators | 帆德制药股份有限公司 | 2017-03-22 | — | — | CN | disclosed |
| EP-2663555-B1 | SUBSTITUTED BENZOAZEPINES AS TOLL-LIKE RECEPTOR MODULATORS | VENTIRX PHARMACEUTICALS INC (US) | 2016-12-14 | — | — | EP | disclosed |
| CN-103562201-B | Substituted benzazepines as modulators of TOLL-like receptors | 帆德制药股份有限公司 | 2016-10-19 | — | — | CN | disclosed |
| US-20140088085-A1 | Substituted Benzoazepines As Toll-Like Receptor Modulators | ARRAY BIOPHARMA, INC (US) | 2014-03-27 | — | — | US | disclosed |
| CN-103562201-A | Substituted benzazepines as modulators of TOLL-like receptors | VENTIRX PHARMACEUTICALS INC | 2014-02-05 | — | — | CN | disclosed |
| EP-2663555-A2 | SUBSTITUTED BENZOAZEPINES AS TOLL-LIKE RECEPTOR MODULATORS | VentiRx Pharmaceuticals, Inc. (US) | 2013-11-20 | — | — | EP | disclosed |
| WO-2012097177-A2 | SUBSTITUTED BENZOAZEPINES AS TOLL-LIKE RECEPTOR MODULATORS | VENTIRX PHARMACEUTICALS, INC. (US) | 2012-07-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140088085-A1 | Substituted Benzoazepines As Toll-Like Receptor Modulators | TLR8, TLR9, TLR1 | CTSK 4172/4885CTSL 4269/4885CTSB 3456/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.