Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | EPAS1 | Q99814 | 12/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | ESPL1 | Q14674 | 1/20 | 0.41 |
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20656774 | 0.84 | ALDH1A1 (0.57) | ALDH1A1EPAS1POLBESPL1PTPRZ1 | |
| SCHEMBL7197925 | 0.82 | ALDH1A1 (0.59) | ALDH1A1EPAS1POLBESPL1PTPRZ1 | |
| SCHEMBL23520947 | 0.81 | LMNA (0.57) | ALDH1A1POLBESPL1LMNASMN1; SMN2 | |
| SCHEMBL714645 | 0.80 | CA2 (0.50) | ALDH1A1EPAS1ESPL1PTPRZ1LMNA | |
| SCHEMBL5526773 | 0.78 | CYP2A6 (0.50) | ALDH1A1CYP2A6LMNAKDM4EMEN1 | |
| SCHEMBL5989844 | 0.78 | ALDH1A1 (0.50) | ALDH1A1EPAS1POLBESPL1PTPRZ1 | |
| SCHEMBL3453385 | 0.77 | EPAS1 (0.49) | ALDH1A1EPAS1ESPL1 | |
| SCHEMBL30487708 | 0.77 | EPAS1 (0.49) | ALDH1A1EPAS1ESPL1 | |
| SCHEMBL3883747 | 0.75 | AKR1C3 (0.49) | ALDH1A1CYP2A6LMNAKDM4EMEN1 | |
| SCHEMBL3882038 | 0.75 | LMNA (0.64) | ALDH1A1CYP2A6LMNAKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2663613-B1 | COMPOUNDS FOR A LIQUID CRYSTALLINE MEDIUM AND USE THEREOF FOR HIGH FREQUENCY COMPONENTS | MERCK PATENT GMBH (DE) | 2016-09-21 | — | — | EP | disclosed |
| US-9175219-B2 | Compounds for a liquid crystalline medium and use thereof for high frequency components | MERCK PATENT GMBH (DE) | 2015-11-03 | — | — | US | disclosed |
| EP-2663613-A1 | COMPOUNDS FOR A LIQUID CRYSTALLINE MEDIUM AND USE THEREOF FOR HIGH FREQUENCY COMPONENTS | Merck Patent GmbH (DE) | 2013-11-20 | — | — | EP | disclosed |
| US-20130277611-A1 | COMPOUNDS FOR A LIQUID CRYSTALLINE MEDIUM AND USE THEREOF FOR HIGH FREQUENCY COMPONENTS | MERCK PATENT GMBH (DE) | 2013-10-24 | — | — | US | disclosed |
| WO-2012095139-A1 | COMPOUNDS FOR A LIQUID CRYSTALLINE MEDIUM AND USE THEREOF FOR HIGH FREQUENCY COMPONENTS | MERCK PATENT GMBH (DE) | 2012-07-19 | — | — | WO | disclosed |