Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.49 |
| ▸ | MMP2 | P08253 | 3/20 | 0.49 |
| ▸ | MMP9 | P14780 | 3/20 | 0.49 |
| ▸ | MMP8 | P22894 | 3/20 | 0.49 |
| ▸ | MMP13 | P45452 | 3/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | NPBWR1 | P48145 | 5/20 | 0.46 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL900987 | 0.85 | RHEB (0.50) | TRPV1MMP2MMP9MMP8MMP13 | |
| SCHEMBL24074309 | 0.83 | KDM4E (0.57) | KDM4EALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL19137950 | 0.83 | TRPV1 (0.56) | KDM4EALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL16121160 | 0.80 | KDM4E (0.45) | KDM4EALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL24075192 | 0.80 | KDM4E (0.57) | KDM4EALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL19175766 | 0.80 | DGAT1 (0.54) | KDM4EALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL19175815 | 0.79 | DGAT1 (0.53) | KDM4EALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL24075326 | 0.77 | KDM4E (0.57) | KDM4EALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL900794 | 0.77 | NPBWR1 (0.74) | TRPV1MMP2MMP9MMP8MMP13 | |
| SCHEMBL10325105 | 0.77 | NPBWR1 (0.58) | TRPV1MMP2MMP9MMP8MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012096813-A1 | IMIDAZOLE DERIVATIVES | MERCK SHARP & DOHME CORP. (US) | 2012-07-19 | — | — | WO | disclosed |