SCHEMBL10326451

SCHEMBL10326451

Cc1cc(C)c(-c2ccc(OC[C@@H]3CCCN3)cc2)c(C)c1

nearest known ligand 0.57

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 9/20 0.54
CHRNA3 P32297 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10326294 1.00 LTA4H (0.54) LTA4HCHRNA3
SCHEMBL10326450 1.00 LTA4H (0.54) LTA4HCHRNA3
SCHEMBL6535790 0.83 LTA4H (0.66) LTA4HCHRNA3
SCHEMBL6535788 0.83 LTA4H (0.66) LTA4HCHRNA3
SCHEMBL10326507 0.83 LTA4H (0.66) LTA4HCHRNA3
SCHEMBL10326841 0.80 CHRNA3 (0.56) LTA4HCHRNA3
SCHEMBL10326825 0.80 CHRNA3 (0.56) LTA4HCHRNA3
SCHEMBL10326519 0.80 CHRNA3 (0.56) LTA4HCHRNA3
SCHEMBL4310569 0.79 LTA4H (0.74) LTA4HCHRNA3
SCHEMBL4310564 0.79 LTA4H (0.74) LTA4HCHRNA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2438989-B1 USE OF ASYMMETRIC HYDROGENATION CATALYST TAKASAGO PERFUMERY CO LTD (JP) 2016-04-13 EP disclosed
US-8217204-B2 Catalyst for asymmetric hydrogenation TAKASAGO INTERNATIONAL CORPORATION (JP) 2012-07-10 US disclosed
US-8217204-B2 Catalyst for asymmetric hydrogenation TAKASAGO INTERNATIONAL CORPORATION (JP) 2012-07-10 US disclosed
US-20100324338-A1 CATALYST FOR ASYMMETRIC HYDROGENATION TAKASAGO INTERNATIONAL CORPORATION (JP) 2010-12-23 US disclosed
US-20100324338-A1 CATALYST FOR ASYMMETRIC HYDROGENATION TAKASAGO INTERNATIONAL CORPORATION (JP) 2010-12-23 US disclosed
WO-2010140636-A1 ASYMMETRIC HYDROGENATION CATALYST 高砂香料工業株式会社 (JP) 2010-12-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100324338-A1 CATALYST FOR ASYMMETRIC HYDROGENATION H1-0, H1-5, ADH5 LTA4H 2091/4885CHRNA3 1704/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.