Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | IAPP | P10997 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 4/20 | 0.44 |
| ▸ | CTSG | P08311 | 4/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | BID | P55957 | 3/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.43 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.43 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | EP300 | Q09472 | 1/20 | 0.43 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.43 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3285467 | 0.83 | GABRA1 (0.64) | IAPPGABRA1GABRB2 | |
| SCHEMBL27540250 | 0.82 | CYP3A4 (0.56) | CYP3A4CYP2D6CYP2C9BIDMCL1 | |
| SCHEMBL201764 | 0.81 | ALOX5 (0.61) | ALOX5PTGS2IAPPELANECTSG | |
| Ammonia Solution, Strong SCHEMBL8748451 | 0.80 | CYP3A4 (0.54) | CYP3A4CYP2D6CYP2C9BIDMCL1 | |
| SCHEMBL1023094 | 0.80 | GABRA1 (0.71) | ALOX5PTGS2IAPPELANECTSG | |
| Hydrogen Sulfide SCHEMBL28293295 | 0.79 | ALOX5 (0.59) | ALOX5PTGS2IAPPCYP3A4CYP2D6 | |
| SCHEMBL1024684 | 0.77 | ALOX5 (0.58) | ALOX5PTGS2IAPPELANECTSG | |
| SCHEMBL19880532 | 0.77 | F7 (0.50) | PTGS2CYP3A4BIDMCL1BCL2L1 | |
| SCHEMBL27568421 | 0.76 | BID (0.50) | IAPPELANECTSGBIDMCL1 | |
| SCHEMBL10475391 | 0.76 | ALOX5 (0.56) | ALOX5PTGS2IAPPELANECTSG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1474377-B1 | NITROSOPHENOLS AND C-NITROSOANILINES AS POLYMERIZATION INHIBITORS | CHEMTURA CORP (US) | 2011-01-19 | — | — | EP | claimed |
| EP-1685183-A2 | METHOD FOR PRODUCING CARBONYL REST-CONTAINING ORGANOSILICON COMPOUNDS | Wacker Chemie AG (DE) | 2006-08-02 | — | — | EP | disclosed |
| WO-2005049697-A2 | METHOD FOR PRODUCING CARBONYL REST-CONTAINING ORGANOSILICON COMPOUNDS | WACKER CHEMIE AG (DE) | 2005-06-02 | — | — | WO | disclosed |
| CN-1205366-A | System for electrochemical delignification of lignincontaining materials and process for its application | CONSORTIUM FURE ELEKTROCHEMISC (DE) | 1999-01-20 | — | — | CN | disclosed |