Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.51 |
| ▸ | DHODH | Q02127 | 3/20 | 0.51 |
| ▸ | ULK1 | O75385 | 1/20 | 0.47 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.45 |
| ▸ | TERT | O14746 | 1/20 | 0.44 |
| ▸ | KHK | P50053 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10106568 | 1.00 | LMNA (0.59) | LMNANPSR1PSMB8DHODHULK1 | |
| SCHEMBL10327137 | 1.00 | LMNA (0.59) | LMNANPSR1PSMB8DHODHULK1 | |
| Hydrochloric Acid SCHEMBL2706941 | 0.98 | LMNA (0.58) | LMNANPSR1PSMB8DHODHULK1 | |
| Hydrochloric Acid SCHEMBL2706945 | 0.98 | LMNA (0.58) | LMNANPSR1PSMB8DHODHULK1 | |
| SCHEMBL20088371 | 0.87 | KDR (0.47) | LMNANPSR1PSMB8DHODHULK1 | |
| SCHEMBL20088373 | 0.87 | KDR (0.47) | LMNANPSR1PSMB8DHODHULK1 | |
| SCHEMBL12295117 | 0.85 | NPSR1 (0.63) | LMNANPSR1PSMB8DHODHULK1 | |
| SCHEMBL17676960 | 0.85 | NPSR1 (0.63) | LMNANPSR1PSMB8DHODHULK1 | |
| SCHEMBL10326684 | 0.85 | NPSR1 (0.63) | LMNANPSR1PSMB8DHODHULK1 | |
| SCHEMBL29697282 | 0.85 | NPSR1 (0.63) | LMNANPSR1PSMB8DHODHULK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2438989-B1 | USE OF ASYMMETRIC HYDROGENATION CATALYST | TAKASAGO PERFUMERY CO LTD (JP) | 2016-04-13 | — | — | EP | disclosed |
| US-8217204-B2 | Catalyst for asymmetric hydrogenation | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2012-07-10 | — | — | US | disclosed |
| US-20100324338-A1 | CATALYST FOR ASYMMETRIC HYDROGENATION | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2010-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100324338-A1 | CATALYST FOR ASYMMETRIC HYDROGENATION | H1-0, H1-5, ADH5 | LMNA 3206/4885NPSR1 2526/4885PSMB8 3775/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.