Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 4/20 | 0.59 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.59 |
| ▸ | F2 | P00734 | 1/20 | 0.59 |
| ▸ | PLG | P00747 | 1/20 | 0.59 |
| ▸ | PLAU | P00749 | 1/20 | 0.59 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.59 |
| ▸ | KLK1 | P06870 | 1/20 | 0.59 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.59 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.47 |
| ▸ | HTR3B | O95264 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.47 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29786166 | 1.00 | GRIN1 (0.59) | GRIN1GRIN2BF2PLGPLAU | |
| SCHEMBL7035626 | 1.00 | GRIN1 (0.59) | GRIN1GRIN2BF2PLGPLAU | |
| SCHEMBL10802010 | 0.83 | LCK (0.62) | GRIN1GRIN2BF2PLGPLAU | |
| SCHEMBL19411892 | 0.82 | F12 (0.60) | GRIN1GRIN2BNPC1RAB9ALMNA | |
| SCHEMBL17666232 | 0.82 | F12 (0.60) | GRIN1GRIN2BNPC1RAB9ALMNA | |
| SCHEMBL2055355 | 0.80 | LMNA (0.45) | GRIN1GRIN2BF2PLGPLAU | |
| SCHEMBL2100967 | 0.80 | LMNA (0.45) | GRIN1GRIN2BF2PLGPLAU | |
| SCHEMBL17988330 | 0.78 | CES2 (0.56) | GRIN1GRIN2BF2PLGPLAU | |
| SCHEMBL23864974 | 0.77 | KDM4E (0.56) | GRIN1GRIN2BPLAUPRSS1RAB9A | |
| SCHEMBL22373743 | 0.77 | PLAU (0.61) | GRIN1GRIN2BF2PLGPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11958815-B1 | N′-(2-(5-phenyl-1,3,4-oxadiazol-2-ylthio)acetoxy)-2-naphthimidamide as antimicrobial compound | King Faisal University (SA) | 2024-04-16 | — | — | US | claimed |
| US-11952354-B1 | 5-((2-isopropyl-5-methylphenoxy)methyl)-3-(naphthalen-2-yl)-1,2,4-oxadiazole as an anti-cancer and antimicrobial compound | King Faisal University (SA) | 2024-04-09 | — | — | US | claimed |
| US-11905262-B1 | N′-(2-(5-(4-chlorophenyl)-1,3,4-oxadiazol-2-ylthio)acetoxy)-2-naphthimidamide as an antimicrobial compound | King Faisal University (SA) | 2024-02-20 | — | — | US | claimed |
| CN-108440440-B | Naphthalene ring-containing 1,2, 4-oxadiazole-cinnamoyl piperazine compound and preparation method and application thereof | 贵州医科大学 | 2021-07-13 | — | — | CN | claimed |
| US-11976051-B1 | N′-(2-(5-(4-chlorophenyl)-1,3,4-oxadiazol-2-ylthio)acetoxy)-2-naphthimidamide as an antimicrobial compound | King Faisal University (SA) | 2024-05-07 | — | — | US | disclosed |
| US-20240122179-A1 | AUXINIC HERBICIDES AND METHODS OF USE THEREOF | CORTEVA AGRISCIENCE LLC (US) | 2024-04-18 | — | — | US | disclosed |
| US-11958815-B1 | N′-(2-(5-phenyl-1,3,4-oxadiazol-2-ylthio)acetoxy)-2-naphthimidamide as antimicrobial compound | King Faisal University (SA) | 2024-04-16 | — | — | US | disclosed |
| US-11952354-B1 | 5-((2-isopropyl-5-methylphenoxy)methyl)-3-(naphthalen-2-yl)-1,2,4-oxadiazole as an anti-cancer and antimicrobial compound | King Faisal University (SA) | 2024-04-09 | — | — | US | disclosed |
| CN-117813004-A | Auxin herbicide and application method thereof | 科迪华农业科技有限责任公司 | 2024-04-02 | — | — | CN | disclosed |
| US-11905262-B1 | N′-(2-(5-(4-chlorophenyl)-1,3,4-oxadiazol-2-ylthio)acetoxy)-2-naphthimidamide as an antimicrobial compound | King Faisal University (SA) | 2024-02-20 | — | — | US | disclosed |
| US-9718784-B2 | Substituted pyrazoles as heat shock transcription factor activators | DUKE UNIVERSITY (US) | 2017-08-01 | — | — | US | disclosed |
| US-9717709-B2 | Substituted pyrazoles as heat shock transcription factor activators | DUKE UNIVERSITY (US) | 2017-08-01 | — | — | US | disclosed |
| WO-2005123703-A2 | ALKYNYL DERIVATIVES AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | ADDEX PHARMACEUTICALS SA (CH) | 2005-12-29 | — | — | WO | disclosed |
| US-6329389-B1 | HETEROCYCLIC AMINES AND DERIVATIVES, SOMATOSTATIN AND ANTIDIABETIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1070054-A1 | AMINE COMPOUNDS, THEIR PRODUCTION AND THEIR USE AS SOMATOSTATIN RECEPTOR ANTAGONISTS OR AGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2001-01-24 | — | — | EP | disclosed |
| WO-1999052875-A1 | AMINE COMPOUNDS, THEIR PRODUCTION AND THEIR USE AS SOMATOSTATIN RECEPTOR ANTAGONISTS OR AGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-10-21 | — | — | WO | disclosed |
| EP-0438230-B1 | Indole-substituted five-membered heteroaromatic compounds | MERCK SHARP & DOHME (GB) | 1997-04-23 | — | — | EP | disclosed |
| US-5317103-A | Migraine treatment | MERCK SHARP & DOHME LIMITED (GB) | 1994-05-31 | — | — | US | disclosed |
| EP-0438230-A2 | Indole-substituted five-membered heteroaromatic compounds | MERCK SHARP & DOHME LTD. (GB) | 1991-07-24 | — | — | EP | disclosed |
| US-4142044-A | FLUORESCENT DYES | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240122179-A1 | AUXINIC HERBICIDES AND METHODS OF USE THEREOF | DDT, HACL2, ALAD | GRIN1 2925/4885GRIN2B 2999/4885F2 4289/4885 |
| US-11905262-B1 | N′-(2-(5-(4-chlorophenyl)-1,3,4-oxadiazol-2-ylthio)acetoxy)-2-naphthimidamide as an antimicrobial compound | NIT2, NOC2L, B3GNT2 | GRIN1 3096/4885GRIN2B 3893/4885F2 4615/4885 |
| US-11958815-B1 | N′-(2-(5-phenyl-1,3,4-oxadiazol-2-ylthio)acetoxy)-2-naphthimidamide as antimicrobial compound | NIT2, NOC2L, NANP | GRIN1 3606/4885GRIN2B 4318/4885F2 4587/4885 |
| US-11976051-B1 | N′-(2-(5-(4-chlorophenyl)-1,3,4-oxadiazol-2-ylthio)acetoxy)-2-naphthimidamide as an antimicrobial compound | NIT2, NOC2L, B3GNT2 | GRIN1 3220/4885GRIN2B 3953/4885F2 4594/4885 |
| US-11952354-B1 | 5-((2-isopropyl-5-methylphenoxy)methyl)-3-(naphthalen-2-yl)-1,2,4-oxadiazole as an anti-cancer and antimicrobial compound | API5, OXA1L, ING2 | GRIN1 3576/4885GRIN2B 4268/4885F2 4798/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.