Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.55 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 11/20 | 0.47 |
| ▸ | FAAH | O00519 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CCR6 | P51684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29189790 | 0.89 | CA12 (0.61) | ALDH1A1HPGDCA12CA1CA9 | |
| SCHEMBL9820253 | 0.87 | ALDH1A1 (0.53) | HSP90AA1TDP1ALDH1A1NPSR1CACNA1B | |
| SCHEMBL300884 | 0.85 | CA12 (0.42) | TDP1ALDH1A1HPGDCA12CA1 | |
| SCHEMBL10328161 | 0.84 | NSD2 (0.53) | HSP90AA1TDP1ALDH1A1NPSR1CACNA1B | |
| SCHEMBL10328160 | 0.84 | NSD2 (0.49) | HSP90AA1TDP1ALDH1A1NPSR1CACNA1B | |
| SCHEMBL15991987 | 0.84 | ALDH1A1 (0.56) | HSP90AA1TDP1ALDH1A1NPSR1CACNA1B | |
| SCHEMBL29354362 | 0.82 | MAPK1 (0.54) | HSP90AA1ALDH1A1HTTMGLLFAAH | |
| SCHEMBL79589 | 0.82 | MAPK1 (0.54) | HSP90AA1ALDH1A1HTTMGLLFAAH | |
| SCHEMBL15991754 | 0.82 | ALDH1A1 (0.47) | HSP90AA1TDP1ALDH1A1NPSR1CACNA1B | |
| SCHEMBL17301093 | 0.81 | KMT2A (0.38) | HSP90AA1TDP1ALDH1A1NPSR1CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220135614-A1 | SYNTHESIS OF BICYCLE TOXIN CONJUGATES, AND INTERMEDIATES THEREOF | Bicyclerd Limited (GB) | 2022-05-05 | — | — | US | disclosed |
| US-9242010-B2 | Living copolymer-protein/peptide hybrids for biomedical applications | RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) | 2016-01-26 | — | — | US | disclosed |
| US-9242010-B2 | Living copolymer-protein/peptide hybrids for biomedical applications | RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) | 2016-01-26 | — | — | US | disclosed |
| WO-2014079890-A1 | TITANATE NANOSTRUCTURE FOR REGENERATING AND ENGINEERING TISSUE | UNIVERSITE DE BOURGOGNE (FR) | 2014-05-30 | — | — | WO | disclosed |
| US-20110262991-A1 | Living Copolymer-Protein/Peptide Hybrids for Biomedical Applications | THE RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK | 2011-10-27 | — | — | US | disclosed |
| US-20090305264-A1 | COOPERATIVE PROBES AND METHODS OF USING THEM | FLUIDIGM CORPORATION | 2009-12-10 | — | — | US | disclosed |
| WO-2009140683-A1 | LIVING COPOLYMER PROTEIN/PEPTIDE HYBRIDS FOR BIOMEDICAL APPLICATIONS | RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) | 2009-11-19 | — | — | WO | disclosed |
| EP-2004861-A2 | COOPERATIVE PROBES AND METHODS OF USING THEM | Arcxis Biotechnologies, Inc. (US) | 2008-12-24 | — | — | EP | disclosed |
| EP-1893741-A1 | CELL-BASED MICROARRAYS, AND METHODS FOR THEIR PREPARATION AND USE | Beckman Coulter, Inc. (US) | 2008-03-05 | — | — | EP | disclosed |
| WO-2007114986-A2 | COOPERATIVE PROBES AND METHODS OF USING THEM | ARCXIS BIOTECHNOLOGIES, INC. (US) | 2007-10-11 | — | — | WO | disclosed |
| US-7262177-B2 | Conjugates of glycosylated/galactosylated peptide, bifunctional linker, and nucleotidic monomers/polymers, and related compositions and methods of use | CELL WORKS THERAPEUTICS, INC. (US) | 2007-08-28 | — | — | US | disclosed |
| US-7262177-B2 | Conjugates of glycosylated/galactosylated peptide, bifunctional linker, and nucleotidic monomers/polymers, and related compositions and methods of use | CELL WORKS THERAPEUTICS, INC. (US) | 2007-08-28 | — | — | US | disclosed |
| WO-2007001817-A1 | CELL-BASED MICROARRAYS, AND METHODS FOR THEIR PREPARATION AND USE | BECKMAN COULTER, INC. (US) | 2007-01-04 | — | — | WO | disclosed |
| US-20060292559-A1 | Cell-based microarrays, and methods for their preparation and use | BECKMAN COULTER, INC. (US) | 2006-12-28 | — | — | US | disclosed |
| EP-0779934-B1 | COMPOSITIONS AND METHODS FOR USE IN DETECTION OF ANALYTES | BECKMAN COULTER INC (US) | 2000-04-05 | — | — | EP | disclosed |
| US-5648213-A | IMMUNOASSAY | BECKMAN INSTRUMENTS, INC. (US) | 1997-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220135614-A1 | SYNTHESIS OF BICYCLE TOXIN CONJUGATES, AND INTERMEDIATES THEREOF | BTD, ANTXR2, CYCS | HSP90AA1 1706/4885TDP1 2483/4885ALDH1A1 3317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.