Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11327997 | 0.63 | TOP2A (0.36) | — | |
| SCHEMBL9881584 | 0.61 | — | — | |
| SCHEMBL19224625 | 0.55 | — | — | |
| SCHEMBL856432 | 0.54 | ALDH1A1 (0.39) | ALDH1A1HPGD | |
| SCHEMBL5323960 | 0.52 | — | — | |
| SCHEMBL24174318 | 0.52 | — | — | |
| SCHEMBL5998917 | 0.52 | — | — | |
| SCHEMBL13943872 | 0.52 | — | — | |
| SCHEMBL8312838 | 0.50 | — | — | |
| SCHEMBL9850249 | 0.50 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8471006-B2 | Coupling agents for peptide synthesis | UNIVERSITY OF MASSACHUSETTS (US) | 2013-06-25 | — | — | US | disclosed |
| US-20120277428-A1 | NEW COUPLING AGENTS FOR PEPTIDE SYNTHESIS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-11-01 | — | — | US | disclosed |
| US-8217169-B2 | Coupling agents for peptide synthesis | UNIVERSITY OF MASSACHUSETTS (US) | 2012-07-10 | — | — | US | disclosed |
| US-20110028720-A1 | New Coupling Agents for Peptide Synthesis | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-02-03 | — | — | US | disclosed |
| US-7812158-B2 | Coupling agents for peptide synthesis | UNIVERSITY OF MASSACHUSETTS (US) | 2010-10-12 | — | — | US | disclosed |
| US-20070112196-A1 | New coupling agents for peptide synthesis | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120277428-A1 | NEW COUPLING AGENTS FOR PEPTIDE SYNTHESIS | NGLY1, NPPA, VIP | ALDH1A1 4753/4885HPGD 827/4885 |
| US-20070112196-A1 | New coupling agents for peptide synthesis | NGLY1, NPPA, VIP | ALDH1A1 4756/4885HPGD 1137/4885 |
| US-20110028720-A1 | New Coupling Agents for Peptide Synthesis | NGLY1, NPPA, VIP | ALDH1A1 4753/4885HPGD 827/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.