Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL813379 | 0.90 | RAB9A (0.58) | TSHRCYP3A4AOC3RAB9AMAPT | |
| SCHEMBL9787713 | 0.87 | TSHR (0.67) | TSHRCYP3A4RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL12604117 | 0.86 | TSHR (0.65) | TSHRCYP3A4AOC3RAB9AMAPT | |
| SCHEMBL13008184 | 0.85 | TSHR (0.59) | TSHRCYP3A4RAB9AMAPTHPGD | |
| SCHEMBL15850712 | 0.84 | TSHR (0.62) | TSHRCYP3A4AOC3MAPTNPC1 | |
| SCHEMBL274924 | 0.83 | TSHR (0.79) | TSHRCYP3A4RAB9AMAPTHPGD | |
| SCHEMBL11915175 | 0.82 | CYP3A4 (0.74) | TSHRCYP3A4MAPTHPGDSMN1; SMN2 | |
| SCHEMBL873550 | 0.81 | TSHR (0.54) | TSHRCYP3A4RAB9AMAPTHPGD | |
| SCHEMBL19566708 | 0.81 | TSHR (0.62) | TSHRCYP3A4MAPTLMNACYP1A2 | |
| SCHEMBL10299631 | 0.81 | KMT2A (0.53) | RAB9AMAPTHPGDSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022263562-A1 | FUNCTIONALIZED Q-D/T-SILOXANE-BASED POLYMERIC MATERIALS AND FORMULATIONS AND METHOD FOR PREPARING SAME | SILOXENE AG (CH) | 2022-12-22 | — | — | WO | disclosed |
| US-10316114-B2 | End-functionalized polymers | BASF SE (DE) | 2019-06-11 | — | — | US | disclosed |
| WO-2017050840-A1 | SYNTHETIC FOAM MATERIAL COMPRISING SILANE-TERMINATED POLYMERS | POLY TERRA INNOVATION GMBH (DE) | 2017-03-30 | — | — | WO | disclosed |
| US-20160152739-A1 | ISOCYANATE/SILOXANE POLYETHER COMPOSITION | EVONIK DEGUSSA GMBH (DE) | 2016-06-02 | — | — | US | disclosed |
| US-20160152739-A1 | ISOCYANATE/SILOXANE POLYETHER COMPOSITION | EVONIK DEGUSSA GMBH (DE) | 2016-06-02 | — | — | US | disclosed |
| WO-2013050273-A1 | LINEAR (PER)FLUOROPOLYETHERS WITH -CF(CF3)COF END GROUPS AND DERIVATIVES THEREOF | SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) | 2013-04-11 | — | — | WO | disclosed |
| US-8278256-B2 | Fluorinated lubricants | SOLVAY SOLEXIS S.P.A. (IT) | 2012-10-02 | — | — | US | disclosed |
| US-8217119-B2 | Additives for halopolymers | SOLVAY SOLEXIS S.P.A. (IT) | 2012-07-10 | — | — | US | disclosed |
| WO-2011120947-A1 | END-FUNCTIONALIZED POLYMERS | BASF SE (DE) | 2011-10-06 | — | — | WO | disclosed |
| US-20100160593-A1 | ISOCYANATO TERMINATED PRECURSOR AND METHOD OF MAKING THE SAME | LEAR CORPORATION (US) | 2010-06-24 | — | — | US | disclosed |
| US-20100069275-A1 | Fluorinated lubricants | SOLVAY SOLEXIS S.P.A. (IT) | 2010-03-18 | — | — | US | disclosed |
| US-7678936-B2 | Isocyanato terminated precursor and method of making the same | LEAR CORPORATION (US) | 2010-03-16 | — | — | US | disclosed |
| US-20090326154-A1 | Additives for Halopolymers | SOLVAY SOLEXIS S.P.A. (IT) | 2009-12-31 | — | — | US | disclosed |
| US-7629483-B2 | Peroxidic perfluoropolyethers | SOLVAY SOLEXIS S.P.A. (IT) | 2009-12-08 | — | — | US | disclosed |
| US-20090054604-A1 | ISOCYANATO TERMINATED PRECURSOR AND METHOD OF MAKING THE SAME | LEAR CORPORATION | 2009-02-26 | — | — | US | disclosed |
| US-20080194881-A1 | Copolymers having functional end groups of sulfonyl fluorides and acyl fluorides; macromer promoters useful for both condensation and addition polymerizations for elastomers and polymershaving a crystal structure; mechanical properties; lubricants for magnetic disks; adhesives | SOLVAY SOLEXIS S.P.A. (IT) | 2008-08-14 | — | — | US | disclosed |
| US-7371900-B2 | Peroxidic perfluoropolyethers | SOLVAY SOLEXIS S.P.A. (IT) | 2008-05-13 | — | — | US | disclosed |
| US-7365229-B2 | Peroxidic perfluoropolyethers | SOLVAY SOLEXIS S.P.A. (IT) | 2008-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054604-A1 | ISOCYANATO TERMINATED PRECURSOR AND METHOD OF MAKING THE SAME | IDH3A, IDH2, CBR3 | TSHR 4562/4885CYP3A4 522/4885AOC3 891/4885 |
| US-20080194881-A1 | Copolymers having functional end groups of sulfonyl fluorides and acyl fluorides; macromer promoters useful for both condensation and addition polymerizations for elastomers and polymershaving a crystal structure; mechanical properties; lubricants for magnetic disks; adhesives | FOXO1, FOXM1, F12 | TSHR 1254/4885CYP3A4 3727/4885AOC3 984/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.