Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.39 |
| ▸ | BRD1 | O95696 | 1/20 | 0.39 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4248062 | 0.99 | MEN1 (0.41) | MEN1KMT2APABPC1LMNASMN1; SMN2 | |
| SCHEMBL1032033 | 0.88 | CACNA1B (0.46) | MEN1KMT2APABPC1LMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4247175 | 0.87 | CACNA1B (0.45) | MEN1KMT2APABPC1LMNASMN1; SMN2 | |
| SCHEMBL1032588 | 0.84 | MEN1 (0.43) | MEN1KMT2APABPC1LMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4244246 | 0.83 | ADRB2 (0.42) | MEN1KMT2APABPC1LMNASMN1; SMN2 | |
| SCHEMBL2466084 | 0.76 | FFAR1 (0.51) | MEN1KMT2ALMNASMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL4914708 | 0.75 | FFAR1 (0.50) | MEN1KMT2ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL2468223 | 0.73 | LMNA (0.46) | LMNASMN1; SMN2ALDH1A1MAPTPKM | |
| SCHEMBL2468236 | 0.70 | ADRB2 (0.48) | LMNASMN1; SMN2ALDH1A1MAPTPKM | |
| Hydrochloric Acid SCHEMBL4925564 | 0.70 | ADRB2 (0.47) | LMNASMN1; SMN2ALDH1A1MAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2013179-B1 | ARYLOXYETHYLAMINE COMPOUNDS SUITABLE FOR TREATING DISORDERS THAT RESPOND TO MODULATION OF THE DOPAMINE D3 RECEPTOR | ABBOTT GMBH & CO KG (DE) | 2011-01-19 | — | — | EP | disclosed |
| EP-2013179-A1 | ARYLOXYETHYLAMINE COMPOUNDS SUITABLE FOR TREATING DISORDERS THAT RESPOND TO MODULATION OF THE DOPAMINE D3 RECEPTOR | Abbott GmbH & Co. KG (DE) | 2009-01-14 | — | — | EP | disclosed |
| WO-2007118859-A1 | ARYLOXYETHYLAMINE COMPOUNDS SUITABLE FOR TREATING DISORDERS THAT RESPOND TO MODULATION OF THE DOPAMINE D3 RECEPTOR | ABBOTT GMBH & CO. KG (DE) | 2007-10-25 | — | — | WO | disclosed |