Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LDHA | P00338 | 2/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1037140 | 0.87 | PTGER4 (0.52) | RAB9ANPC1CYP1A2CYP2C19RECQL | |
| SCHEMBL10328616 | 0.86 | RXRA (0.52) | RAB9ANPC1CYP1A2CYP2C19RECQL | |
| SCHEMBL3334602 | 0.86 | NPC1 (0.67) | RAB9ANPC1CYP1A2CYP2C19RECQL | |
| SCHEMBL10328542 | 0.86 | MRGPRX4 (0.50) | RAB9ANPC1CYP1A2CYP2C19RECQL | |
| SCHEMBL10328594 | 0.86 | MEN1 (0.50) | RAB9ANPC1CYP1A2CYP2C19RECQL | |
| SCHEMBL10328621 | 0.86 | NPC1 (0.53) | RAB9ANPC1CYP1A2CYP2C19RECQL | |
| SCHEMBL17112794 | 0.84 | NPC1 (0.51) | RAB9ANPC1CYP1A2CYP2C19RECQL | |
| SCHEMBL9356623 | 0.84 | RAB9A (0.52) | RAB9ANPC1CYP1A2CYP2C19RECQL | |
| SCHEMBL13302166 | 0.83 | RAB9A (0.47) | RAB9ANPC1CYP1A2CYP2C19RECQL | |
| SCHEMBL10328539 | 0.83 | PTGER4 (0.49) | RAB9ANPC1CYP1A2CYP2C19RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2120923-B1 | USE OF SUBSTITUTED PYRANONE ACID DERIVATIVES FOR THE TREATMENT OF METABOLIC SYNDROME | SANOFI SA (FR) | 2012-07-18 | — | — | EP | disclosed |
| WO-2008086949-A1 | USE OF SUBSTITUTED PYRANONE ACID DERIVATIVES FOR THE TREATMENT OF METABOLIC SYNDROME | SANOFI-AVENTIS (FR) | 2008-07-24 | — | — | WO | disclosed |