Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 1/20 | 0.52 |
| ▸ | LDHA | P00338 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | EDNRA | P25101 | 1/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8160885 | 0.88 | CYP2C19 (0.51) | LDHAMEN1KMT2ANPC1CYP1A2 | |
| SCHEMBL10328650 | 0.87 | RAB9A (0.50) | PTGER4LDHAMEN1KMT2ANPC1 | |
| SCHEMBL10328594 | 0.87 | MEN1 (0.50) | PTGER4LDHAMEN1KMT2ANPC1 | |
| SCHEMBL10328542 | 0.87 | MRGPRX4 (0.50) | PTGER4NPC1CYP1A2CYP2C19RECQL | |
| SCHEMBL10548799 | 0.87 | HPGD (0.51) | LDHAMEN1KMT2ANPC1CYP1A2 | |
| SCHEMBL10328621 | 0.87 | NPC1 (0.53) | PTGER4LDHAMEN1KMT2ANPC1 | |
| SCHEMBL3334602 | 0.87 | NPC1 (0.67) | PTGER4LDHAMEN1KMT2ANPC1 | |
| SCHEMBL10328598 | 0.86 | LDHA (0.54) | LDHAMEN1KMT2ANPC1RAB9A | |
| SCHEMBL10328647 | 0.86 | MEN1 (0.70) | LDHAMEN1KMT2AMAOBNR4A2 | |
| SCHEMBL10328616 | 0.85 | RXRA (0.52) | PTGER4LDHAMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105481812-B | Preparation method of 5-benzyloxy-4-oxo-4H-pyran-2-carboxylic acid | 重庆天奕恒化科技有限公司 | 2020-04-21 | — | — | CN | claimed |
| CN-105481812-A | 5-benzyloxy-4-oxo-4H-pyran-2-carboxylic acid preparation method | CHONGQING TIANYI HENGHUA TECH CO LTD | 2016-04-13 | — | — | CN | claimed |
| CN-116669727-A | Triazole-pyridinyl substituted azacyclohexylacetic acid compounds as LPA receptor antagonists | 唯久生物有限公司 | 2023-08-29 | — | — | CN | disclosed |
| EP-4196220-A1 | TRIAZOLE-PYRIDINYL SUBSTITUTED AZACYCLOHEXYL ACETIC ACID COMPOUNDS AS LPA RECEPTOR ANTAGONISTS | Viva Star Biosciences Limited (HK) | 2023-06-21 | — | — | EP | disclosed |
| US-20220402873-A1 | NOVEL P62 LIGAND COMPOUND, AND COMPOSITION CONTAINING SAME FOR PREVENTING, AMELIORATING, OR TREATING PROTEINOPATHIES | AUTOTAC INC. (KR) | 2022-12-22 | — | — | US | disclosed |
| US-20220402873-A1 | NOVEL P62 LIGAND COMPOUND, AND COMPOSITION CONTAINING SAME FOR PREVENTING, AMELIORATING, OR TREATING PROTEINOPATHIES | AUTOTAC INC. (KR) | 2022-12-22 | — | — | US | disclosed |
| WO-2022034568-A1 | TRIAZOLE-PYRIDINYL SUBSTITUTED AZACYCLOHEXYL ACETIC ACID COMPOUNDS AS LPA RECEPTOR ANTAGONISTS | VIVA STAR BIOSCIENCES LIMITED (CN) | 2022-02-17 | — | — | WO | disclosed |
| WO-2021054804-A1 | NOVEL P62 LIGAND COMPOUND, AND COMPOSITION CONTAINING SAME FOR PREVENTING, AMELIORATING, OR TREATING PROTEINOPATHIES | 주식회사 오토텍바이오 | 2021-03-25 | — | — | WO | disclosed |
| EP-2542076-B1 | INHIBITORS OF CATECHOL O-METHYL TRANSFERASE AND THEIR USE IN THE TREATMENT OF PSYCHOTIC DISORDERS | MERCK SHARP & DOHME (US) | 2021-01-13 | — | — | EP | disclosed |
| CN-105481812-B | Preparation method of 5-benzyloxy-4-oxo-4H-pyran-2-carboxylic acid | 重庆天奕恒化科技有限公司 | 2020-04-21 | — | — | CN | disclosed |
| CN-105481812-B | Preparation method of 5-benzyloxy-4-oxo-4H-pyran-2-carboxylic acid | 重庆天奕恒化科技有限公司 | 2020-04-21 | — | — | CN | disclosed |
| EP-0243924-B1 | 2-OXO-1-(SUBSTITUTED PHOSPHOROUS)AZETIDINES | E.R. Squibb & Sons, Inc. (US) | 1992-12-23 | — | — | EP | disclosed |
| EP-0209751-B1 | CEPHALOSPORIN DERIVATIVES AND BACTERICIDES CONTAINING THE SAME | MEIJI SEIKA KAISHA LTD. (JP) | 1992-09-16 | — | — | EP | disclosed |
| US-4758557-A | Cephalosporin derivatives and bactericides containing the same | MEIJI SEIKA KAISHA, LTD. (JP) | 1988-07-19 | — | — | US | disclosed |
| US-4743685-A | 2-oxo-1-[[(substituted sulfonyl)amino]carbonyl]azetidines | E. R. SQUIBB & SONS, INC. (US) | 1988-05-10 | — | — | US | disclosed |
| US-4723002-A | 1-(substituted phosphorous)-azetidinone antibacterials | E. R. SQUIBB & SONS, INC. | 1988-02-02 | — | — | US | disclosed |
| EP-0243924-A2 | 2-Oxo-1-(substituted phosphorous)azetidines | E.R. Squibb & Sons, Inc. (US) | 1987-11-04 | — | — | EP | disclosed |
| EP-0209751-A2 | Cephalosporin derivatives and bactericides containing the same | MEIJI SEIKA KAISHA LTD. (JP) | 1987-01-28 | — | — | EP | disclosed |
| US-4632985-A | 3-acylamino-2-oxo-1-azetidinesulfonic acids | E. R. SQUIBB & SONS, INC. (US) | 1986-12-30 | — | — | US | disclosed |
| EP-0204207-A1 | 3-acylamino-2-oxo-1-azetidinesulfonic acids | E.R. Squibb & Sons, Inc. (US) | 1986-12-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220402873-A1 | NOVEL P62 LIGAND COMPOUND, AND COMPOSITION CONTAINING SAME FOR PREVENTING, AMELIORATING, OR TREATING PROTEINOPATHIES | SQSTM1, ATG7, ATG13 | PTGER4 4432/4885LDHA 2555/4885MEN1 2082/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.